87918

Tetramethylrhodamine isothiocyanate mixed isomers

suitable for fluorescence, mixture of isomers

• Synonym(s): MRITC, TRITC, Tetramethylrhodamine B isothiocyanate
• Empirical Formula (Hill Notation): C₂₅H₂₁N₃O₃S
• CAS Number: 95197-95-8
• Molecular Weight: 443.52
• MDL number: MFCD00002867
• NACRES: NA.32
• UNSPSC Code: 12352116

Properties

• Quality Segment: 200
• form: powder
• solubility: DMSO: soluble, methanol: soluble
• fluorescence: λ_ex 529 nm; λ_em 596 nm in DMSO
• suitability: suitable for fluorescence
• storage temp.: 2-8°C

Description

General description

Tetramethylrhodamine isothiocyanate, also known as TRITC is a fluorescent antibody labelling agent. It is a red-fluorescing marker and can be tracked through fluorescence microscopy.[1]

TRITC dissolves completely in DMSO at a rapid rate. And gamma globulin is unaffected to up to 30% DMSO dilution in carbonate buffer. Tetramethylrhodamine isothiocyanate doesn’t dissolve in other denaturing agents completely.[2]

Application

Tetramethylrhodamine isothiocyanate or TRITC is used for tracking the pathway of calcium phosphate/DNA nanoparticles during cell transfection. [1]It is an extremely intensive fluorochrome used for labeling antibodies.

Other Notes

An extremely intensive fluorochrome for labeling antibodies[3]

Safety Information

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H315,H317,H319,H334,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves