Key Documents

6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride

Name: 6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3(7<I>H</I>)-one hydrochloride
Brand: SIGMA

suitable for chemiluminescence, ≥98.0% (HPLC)

Synonym(s):

2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride, Cypridina Luciferin methoxy-analogue, MCLA

About This Item

Empirical Formula (Hill Notation):

C₁₄H₁₃N₃O₂ · HCl

CAS Number:

128322-44-1

Molecular Weight:

291.73

UNSPSC Code:

12352200

NACRES:

NA.32

PubChem Substance ID:

57653269

MDL number:

MFCD00144728

Beilstein/REAXYS Number:

5838857

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Properties

description

luminescence test: Em_max465 nm, 0.1 M Tris pH 8.5; after addition of H₂O₂ (Chemiluminescence: in 0.1 M Tris pH 8.5; after addition of H₂O₂)

assay

≥98.0% (HPLC)

form

powder

solubility

DMSO: soluble, H₂O: soluble

suitability

suitable for chemiluminescence

SMILES string

Cl[H].COc1ccc(cc1)C2=CN3C(=O)C(C)=NC3=CN2

InChI

1S/C14H13N3O2.ClH/c1-9-14(18)17-8-12(15-7-13(17)16-9)10-3-5-11(19-2)6-4-10;/h3-8,15H,1-2H3;1H

InChI key

KGMPQNFFCUDXSO-UHFFFAOYSA-N

Description

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Generation of chemiluminescence by reaction with super oxide O₂^– or singlet oxygen. Used in research of leucocyte function[1][2][3].

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Sodium Lauryl Sulfate Stimulates the Generation of Reactive Oxygen Species through Interactions with Cell Membranes.

Taeko Mizutani et al.

Journal of oleo science, 65(12), 993-1001 (2016-11-11)

Sodium lauryl sulfate (SLS), a representative anionic surfactant, is well-known to induce rough skin following single or multiple topical applications. The mechanism by which SLS induces rough skin is thought to result from the disruption of skin moisture function consisting

Structure-Dependent Effects of Bisphosphonates on Inflammatory Responses in Cultured Neonatal Mouse Calvaria.

Keiko Suzuki et al.

Antioxidants (Basel, Switzerland), 9(6) (2020-06-13)

Bisphosphonates (BPs) are classified into two groups, according to their side chain structures, as nitrogen-containing BPs (NBPs) and non-nitrogen-containing BPs (non-NBPs). In this study, we examined the effects of NBPs and non-NBPs on inflammatory responses, by quantifying the inflammatory mediators

Species-specific control of external superoxide levels by the coral holobiont during a natural bleaching event.

Julia M Diaz et al.

Nature communications, 7, 13801-13801 (2016-12-08)

The reactive oxygen species superoxide (O2·-) is both beneficial and detrimental to life. Within corals, superoxide may contribute to pathogen resistance but also bleaching, the loss of essential algal symbionts. Yet, the role of superoxide in coral health and physiology

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Global Trade Item Number

SKU	GTIN
87787-10MG-F	04061833278383

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