51010
4-Methylumbelliferyl 4-guanidinobenzoate hydrochloride hydrate
≥85% (HPLC)
Synonym(s):
4-Guanidinobenzoic acid 4-methylumbelliferyl ester hydrochloride, MUGB
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About This Item
Empirical Formula (Hill Notation):
C18H15N3O4 · HCl · xH2O
CAS Number:
Molecular Weight:
373.79 (anhydrous basis)
UNSPSC Code:
12352204
PubChem Substance ID:
EC Number:
251-871-0
MDL number:
assay
≥85% (HPLC)
form
powder
fluorescence
λex 323 nm; λem 464 nm (solvent pH 6.0), λex 360 nm; λem 449 nm (Reaction Product)
storage temp.
2-8°C
SMILES string
Cl[H].CC1=CC(=O)Oc2cc(OC(=O)c3ccc(NC(N)=N)cc3)ccc12
InChI
1S/C18H15N3O4.ClH/c1-10-8-16(22)25-15-9-13(6-7-14(10)15)24-17(23)11-2-4-12(5-3-11)21-18(19)20;/h2-9H,1H3,(H4,19,20,21);1H
InChI key
DAFWZROYEOVJAL-UHFFFAOYSA-N
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Some sensitive methods for the assay of trypsinlike enzymes.
P L Coleman et al.
Methods in enzymology, 45, 12-26 (1976-01-01)
Lambro A Johnson et al.
Analytical biochemistry, 608, 113907-113907 (2020-08-20)
Snake venom prothrombin activators such as Ecarin are readily assayed by continuous spectrophotometric monitoring of p-nitroaniline production in a one step assay containing prothrombin and a p-nitroanilide peptide substrate for thrombin. The coupled reactions result in accelerating p-nitroaniline (pNA) production
G W Jameson et al.
The Biochemical journal, 131(1), 107-117 (1973-01-01)
Several esters of 4-methylumbelliferone and 2-naphthol were synthesized and examined as possible spectrofluorimetric titrants for bovine alpha-chymotrypsin, trypsin, thrombin, Factor Xa and for subtilisin Novo. 4-Methylumbelliferyl p-guanidinobenzoate hydrochloride (MUGB) is a satisfactory titrant for alpha- and beta-trypsin, thrombin and Factor
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 51010-250MG | 04061832904115 |
| 51010-1G | 04061826651797 |