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50187

Ammonium 2-(methylthio)ethanesulfonate

≥97.0% (TLC)

Synonym(s):

Methyl coenzyme M ammonium salt

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About This Item

Empirical Formula (Hill Notation):
C3H11NO3S2
CAS Number:
Molecular Weight:
173.25
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:


Quality Segment

assay

≥97.0% (TLC)

SMILES string

N.CSCCS(O)(=O)=O

InChI

1S/C3H8O3S2.H3N/c1-7-2-3-8(4,5)6;/h2-3H2,1H3,(H,4,5,6);1H3

InChI key

FSGSBLDVKBYXIK-UHFFFAOYSA-N

Application

Ammonium 2-(methylthio)ethanesulfonate (Methyl coenzyme M) is converted into methane by the enzyme Methyl-coenzyme M reductase (MCR) derived from methanogenic archaea. Methy-coenzyme M is used in studies on methanogenic (methane-producing) enzymatic processes.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Evert C Duin et al.
Methods in enzymology, 494, 159-187 (2011-03-16)
Methyl-coenzyme M reductase catalyzes the reversible synthesis of methane from methyl-coenzyme M in methanogenic and ANME-1 and ANME-2 Archaea. The purification procedure for methyl-coenzyme M reductase from Methanothermobacter marburgensis is described. The procedure is an accumulation of almost 30 years
R Hedderich et al.
European journal of biochemistry, 193(1), 255-261 (1990-10-05)
The reduction of the heterodisulfide of coenzyme M (H-S-CoM) and 7-mercaptoheptanoyl-L-threonine phosphate (H-S-HTP) is a key reaction in the metabolism of methanogenic bacteria. The heterodisulfide reductase catalyzing this step was purified 80-fold to apparent homogeneity from Methanobacterium thermoautotrophicum. The native
B Solow et al.
Archives of biochemistry and biophysics, 345(2), 299-304 (1997-10-06)
The biochemical mechanism for the formation of the amide bond in N-(7-mercaptoheptanoyl)-L-threonine phosphate (HS-HTP) has been studied by measuring the incorporation of L-[3-(3)H]threonine into N-(7-mercaptoheptanoyl)-L-threonine (HS-HT) by cell extracts (CE) of Methanosarcina thermophila incubated with different precursors. Synthesis of HS-HT



Global Trade Item Number

SKUGTIN
50187-10MG04061832860282
50187-50MG04061832860299

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