The molecular weight for this product is not analyzed on a lot to lot basis. However, the expected range is 500,000 to 700,000 g/mol.
48165
Chitosan from crab shells
highly viscous
Synonym(s):
2-Amino-2-deoxy-(1→4)-β-D-glucopyranan, Poly-(1,4-β-D-glucopyranosamine)
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About This Item
To inquire about this product 48165, please contact your local Merck office or dealer. Contact Technical Service
Recommended Products
biological source
(crab)
form
powder
impurities
≤1% insoluble matter
ign. residue
≤2% (as SO4)
loss
≤12% loss on drying
color
yellow
viscosity
>400 mPa.s, 1 % in acetic acid(20 °C)
InChI
1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1
InChI key
FLASNYPZGWUPSU-SICDJOISSA-N
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General description
Chitosan is a linear amino polysaccharide composed of approximately 20% β1,4-linked N-acetyl-D-glucosamine (GlcNAc) and approximately 80% β1,4-linked D-glucosamine (GlcN) that is prepared by the partial deacetylation of chitin in hot alkali.
Application
Chitosan is a biocompatible, antibacterial, and biodegradable polyelectrolyte with a variety of industrial and biomedical applications. Its chemical properties and low toxicity make it particularly suitable as a component of drug and gene delivery systems, and for the development of biodegradable films and scaffolds for tissue engineering.
Other Notes
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class Code
11 - Combustible Solids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Kyriaki G Zinoviadou et al.
Food & function, 3(3), 312-319 (2012-02-03)
Oil-in-water emulsions (10% w/w n-tetradecane) were prepared at pH = 5.7 by using, as surface active agents, electrostatically formed complexes of sodium stearoyl lactylate (SSL) at a concentration of 0.4% (w/w) and chitosan (CH) in a concentration range between 0
Rushita Shah et al.
Polymers, 11(12) (2019-12-19)
The application of polymeric biomaterial scaffolds utilizing crosslinking strategy has become an effective approach in these days. In the present study, the development and characterization of collagen-chitosan hydrogel film has been reported on using dual crosslinking agent's, i.e., tannic acid
Stephanie Supper et al.
Expert opinion on drug delivery, 11(2), 249-267 (2013-12-07)
Thermogelling chitosan (CS)/glycerophosphate (GP) solutions have been reported as a new type of parenteral in situ forming depot system. These free-flowing solutions at ambient temperature turn into semi-solid hydrogels after parenteral administration. Formulation parameters such as CS physico-chemical characteristics, CS/gelling
Rosanne Raftery et al.
Molecules (Basel, Switzerland), 18(5), 5611-5647 (2013-05-17)
Gene therapy involves the introduction of foreign genetic material into cells in order exert a therapeutic effect. The application of gene therapy to the field of orthopaedic tissue engineering is extremely promising as the controlled release of therapeutic proteins such
Héloïse Ragelle et al.
Journal of controlled release : official journal of the Controlled Release Society, 172(1), 207-218 (2013-08-24)
Recently, chitosan has attracted significant attention in the formulation of small interfering RNA (siRNA). Because of its cationic nature, chitosan can easily complex siRNA, thus readily forming nanoparticles. Moreover, chitosan is biocompatible and biodegradable, which make it a good candidate
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What is the molecular weight of this chitosan (ref 48165)?
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Greetings I wish to know if this chitosan is soluble or insoluble in water. I also realized that there is water-soluble chitosan. Please kindly clarify the difference. I need them to do laboratory experiments.
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This product has not been tested for it's solubility in water. However, one gram chitosan can be dissolved in a mixture of 100mL 10% acetic acid and 50mL methanol, and then precipitated from a precipitant consisted of 10mL ethanol and 90mL acetate ester. The treated chitosan should become soluble in acid-free water completely at 8.02mg/mL
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