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Merck

37970

5,7-Dihydroxytryptamine creatinine sulfate salt

≥97.0% (HPLC)

Synonym(s):

5,7-DHT, 7-Hydroxyserotonin creatinine sulfate salt

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About This Item

Empirical Formula (Hill Notation):
C10H12N2O2 · C4H7N3O · H2SO4
CAS Number:
Molecular Weight:
403.41
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
8817524
MDL number:
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assay

≥97.0% (HPLC)

shipped in

wet ice

storage temp.

−20°C

SMILES string

OS(O)(=O)=O.CN1CC(=O)N=C1N.NCCc2c[nH]c3c(O)cc(O)cc23

InChI

1S/C10H12N2O2.C4H7N3O.H2O4S/c11-2-1-6-5-12-10-8(6)3-7(13)4-9(10)14;1-7-2-3(8)6-4(7)5;1-5(2,3)4/h3-5,12-14H,1-2,11H2;2H2,1H3,(H2,5,6,8);(H2,1,2,3,4)

InChI key

BXYXUOWJXUUTQZ-UHFFFAOYSA-N

Biochem/physiol Actions

Neurotoxin that is relatively selective for serotonergic terminals in adults and gives long-lasting destruction of serotonergic neurons when given neonatally; adrenergic neurotoxicity can be blocked by pretreating with desipramine.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Hai Lin et al.
Neuroscience letters, 598, 91-95 (2015-05-20)
Although tianeptine, an atypical antidepressant has been reported to have antinociceptive effects, the mode of action is different from that of tricyclic antidepressants despite structural similarities. We examined the antiallodynic effect of intrathecal tianeptine in neuropathic pain rats and determined
Victoria M Smith et al.
The European journal of neuroscience, 42(10), 2805-2817 (2015-10-13)
Light serves as the primary stimulus that synchronizes the circadian clock in the suprachiasmatic nucleus (SCN) to the external day/night cycle. Appropriately timed light exposure can reset the phase of the circadian clock. Some serotonergic drugs that bind to the
Jun-Qi Yao et al.
Neuropharmacology, 178, 108230-108230 (2020-07-22)
Anxiety disorders are the most prevalent group of mental disorders globally, leading to considerable losses in health, functioning and increase of medical costs. Till now, the search for novel pharmacological treatments is driven by the growing medical need to improve



Global Trade Item Number

SKUGTIN
469971-1G04061826222324