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Choline chloride

Name: Choline chloride
Brand: SIGMA
Price: 458 PLN

BioUltra, ≥99.0% (AT)

Synonym(s):

(2-Hydroxyethyl)trimethylammonium chloride

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Pack Size	SKU	Availability	Price
25 g		Please contact Customer Service for Availability	PLN 458.00
100 g		Please contact Customer Service for Availability	PLN 1,340.00 PLN 1,005.00

About This Item

Linear Formula:

(CH₃)₃N(Cl)CH₂CH₂OH

CAS Number:

67-48-1

Molecular Weight:

139.62

UNSPSC Code:

12352211

NACRES:

NA.25

PubChem Substance ID:

57648187

EC Number:

200-655-4

Beilstein/REAXYS Number:

3563126

MDL number:

MFCD00011721

Assay:

≥99.0% (AT)

Grade:

reagent grade

Form:

powder or crystals

Solubility:

H₂O: 1 M, clear, colorless

PLN 458.00

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Properties

biological source

synthetic

Quality Level

200

grade

reagent grade

product line

BioUltra

assay

≥99.0% (AT)

form

powder or crystals

impurities

insoluble matter, passes filter test

color

colorless to white

pH

5.0-7.5 (25 °C, 1 M in H₂O)

mp

302-305 °C (dec.) (lit.)

solubility

H₂O: 1 M, clear, colorless

anion traces

sulfate (SO₄^2-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

1 M in H₂O

UV absorption

λ: 260 nm A_max: 0.015, λ: 280 nm A_max: 0.010

SMILES string

[Cl-].C[N+](C)(C)CCO

InChI

1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

InChI key

SGMZJAMFUVOLNK-UHFFFAOYSA-M

Description

General description

Choline acetyltransferase substrate

Biochem/physiol Actions

Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.

Other Notes

Restores cholinergic, biochemical and pharmacological activities in striata of decorticated rats[1]

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Show Differences

1 of 1

This Item	C7527	C7527	C1879
Sigma-Aldrich 26978 Choline chloride	Sigma-Aldrich C7527 Choline chloride	Sigma-Aldrich C7527 Choline chloride	Sigma-Aldrich C1879 Choline chloride
form powder or crystals	form crystals	form crystals	form powder or crystals
assay ≥99.0% (AT)	assay ≥98%	assay ≥98%	assay ≥98%
solubility H₂O: 1 M, clear, colorless	solubility H₂O: 50 mg/mL	solubility H₂O: 50 mg/mL	solubility -
Quality Level 200	Quality Level 300	Quality Level 300	Quality Level 200
grade reagent grade	grade -	grade -	grade -
impurities insoluble matter, passes filter test	impurities -	impurities -	impurities -
form powder or crystals	form crystals	form crystals	form powder or crystals
assay ≥99.0% (AT)	assay ≥98%	assay ≥98%	assay ≥98%
solubility H₂O: 1 M, clear, colorless	solubility H₂O: 50 mg/mL	solubility H₂O: 50 mg/mL	solubility -
Quality Level 200	Quality Level 300	Quality Level 300	Quality Level 200
grade reagent grade	grade -	grade -	grade -
impurities insoluble matter, passes filter test	impurities -	impurities -	impurities -

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Treatment with oxiracetam or choline restores cholinergic biochemical and pharmacological activities in striata of decorticated rats.

S Consolo et al.

Journal of neurochemistry, 54(2), 571-577 (1990-02-01)

Interruption of the corticostriatal pathway by undercutting the frontal cortex resulted after 2 weeks in a 40% reduction of basal acetylcholine (ACh) release in vivo, and in inhibition of the striatal sodium-dependent high-affinity uptake of choline (SDHACU) to the same

The choline transporter-like family SLC44: properties and roles in human diseases.

Elisabeth Traiffort et al.

Molecular aspects of medicine, 34(2-3), 646-654 (2013-03-20)

The Na(+)-independent, high affinity choline carrier system proposed to supply choline for the synthesis of cell membrane phospholipids was recently associated with SLC44 family members (SLC44A1-5) also called choline-like transporter family. SLC44A1 is widely expressed throughout the nervous system in

Role of ¹⁸F-choline PET/CT in suspicion of relapse following definitive radiotherapy for prostate cancer.

Sotirios Chondrogiannis et al.

European journal of nuclear medicine and molecular imaging, 40(9), 1356-1364 (2013-05-15)

The aims of the study were (a) to evaluate the diagnostic role, by means of positive detection rate (PDR), of ¹⁸F-choline (CH) positron emission tomography (PET)/CT in patients with prostate cancer treated with radiotherapy, with curative intent, and suspicion of

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Global Trade Item Number

SKU	GTIN
26978-25G	04061826141618
26978-100G	04061826141601

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