09969

SQ-NHS

suitable for fluorescence, >50% (coupling to amines)

• Synonym(s): Squarain-carboxylate N-succinimidyl ester
• Empirical Formula (Hill Notation): C₃₄H₃₂ClN₃O₆
• CAS Number: 154161-81-6
• Molecular Weight: 614.09
• MDL number: MFCD03792601
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• Assay: >50% (coupling to amines)
• solubility: DMF: soluble
• fluorescence: λ_ex 600 nm; λ_em 645 nm in 0.1 M phosphate pH 7.0
• suitability: suitable for fluorescence
• storage temp.: 2-8°C
• InChI: 1S/C34H32ClN3O6/c1-7-37-25-10-8-18(32(43)44-38-28(39)12-13-29(38)40)14-22(25)34(4,5)27(37)17-21-30(41)20(31(21)42)16-26-33(2,3)23-15-19(35)9-11-24(23)36(26)6/h8-11,14-17H,7,12-13H2,1-6H3
• InChI key: RRLJXAKQFSXTLC-UHFFFAOYSA-N

Description

Application

SQ-NHS contains a reactive N-hydroxysuccinimide group, which allows for coupling with amino groups. When conjugated with proteins, SQ-NHS demonstrates a high quantum yield with an absorption maximum at 640 nm and a nanosecond lifetime. Additionally, in the physiological pH range (6-9), the absorbance, emission, and lifetime of SQ-NHS are pH-independent. It is water insoluble .

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves