902292

EvanPhos

≥95%, powder or crystals

• Synonym(s): Biaryl phosphine ligand for Pd catalysis, Dicyclohexyl(2,6-dimethoxy-3-(2-methoxynaphthalen-1-yl)phenyl)phosphane
• Empirical Formula (Hill Notation): C₃₁H₃₉O₃P
• CAS Number: 2223634-83-9
• Molecular Weight: 490.61
• MDL number: MFCD32068358
• UNSPSC Code: 12161600
• NACRES: NA.22

Properties

• Product Name: EvanPhos, ≥95%
• product line: Buchwald Ligand
• assay: ≥95%
• form: powder or crystals
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: ligand; reaction type: Cross Couplings
• greener alternative product characteristics: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• mp: 131-133 °C
• functional group: phosphine
• greener alternative category: Aligned,
• SMILES string: P(C5CCCCC5)(C4CCCCC4)c1c(c(ccc1OC)c2c3c(ccc2OC)cccc3)OC
• InChI key: IJZUTUMBEYLTNN-UHFFFAOYSA-N

Description

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

Application

EvanPhos is a new biaryl phosphine ligand designed in the Lipshutz Lab as a Pd-complexed pre-catalyst for Suzuki-Miyaura cross couplings. Micellar catalysis was demonstrated with the surfactant TPGS-750-M, 2 wt. % in H₂O (cat# 733857) and is an attractive technology for greener chemistry.

Other Notes

EvanPhos: a ligand for ppm level Pd-catalyzed Suzuki–Miyaura couplings in either organic solvent or water

Watch Professor Lipshutz talk about greener chemistry in this webinar: From milligrams to kilograms: synthetic chemistry following nature′s lead

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable