733857
DL-α-Tocopherol methoxypolyethylene glycol succinate solution
2 wt. % in H2O
Synonym(s):
Polyethylene glycol, TPGS-750-M
About This Item
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form
liquid
Quality Level
reaction suitability
reagent type: catalyst
reaction type: Bucherer Carbazole Synthesis
reagent type: surfactant
greener alternative product characteristics
Catalysis
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sustainability
Greener Alternative Product
concentration
2 wt. % in H2O
refractive index
n20/D 1.336
density
1.002 g/mL at 25 °C
greener alternative category
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General description
Application
Included among the possible reactions are:
- Olefin metathesis
- Pd-catalyzed cross coupling reactions including Heck, Suzuki-Miyaura, Sonogashira and Buchwald-Hartwig reactions
- C-H activation reactions
Second generation amphiphile for cross-coupling reactions in water
Other Notes
From milligrams to kilograms: synthetic chemistry following nature′s lead
related product
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Articles
Lipshutz and co-workers have recently developed a second generation technology to their original PTS-enabling surfactant based on the polyoxyethanyl-α-tocopheryl succinate derivative, TPGS-750-M.
Surfactants for efficient reactions in water as a green chemistry alternative.
A variety of palladium-catalyzed cross-coupling reactions can be run under room temperature conditions in water with TPGS- 750-M, using a variety of commercially available palladium complexes and ligands.
Protocols
TPGS-750-M surfactant enables various reactions in water at room temperature, enhancing efficiency and versatility in synthesis.
Related Content
Prof. Bruce Lipshutz and co-workers have developed designer surfactants to allow several classes of transformations (e.g. Suzuki-Miyaura, Olefin Metathesis, 1,4-Addition to Enones, etc.) to be performed in water.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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