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733857

DL-α-Tocopherol methoxypolyethylene glycol succinate solution

greener alternative

2 wt. % in H2O, liquid

Synonym(s):

Polyethylene glycol, TPGS-750-M

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Pack SizeSKUAvailabilityPrice
1.5 mL
Please contact Customer Service for Availability
$18.40
10 mL
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$47.00
50 mL
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$180.00
100 mL
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$237.00
500 mL
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$795.00
1 L
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$934.00

About This Item

Linear Formula:
(C2H4O)nC34H56O5
CAS Number:
MDL number:
NACRES:
NA.22
UNSPSC Code:
51171641

$18.40


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Product Name

DL-α-Tocopherol methoxypolyethylene glycol succinate solution, 2 wt. % in H2O

form

liquid

Quality Level

reaction suitability

reagent type: catalyst
reaction type: Bucherer Carbazole Synthesis, reagent type: surfactant

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

concentration

2 wt. % in H2O

refractive index

n20/D 1.336

density

1.002 g/mL at 25 °C

greener alternative category

General description

Learn More at the Professor and Product Portal of Professor Bruce Lipshutz.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product TPGS-750-M is a lead surfactant for many transition metal-catalyzed cross-couplings and has been enhanced for catalytic efficiency. Find details here.

Application

Second generation amphiphile which forms micelles upon dissolution in water allowing a variety of cross-coupling reactions to take place in water instead of organic solvent.

Included among the possible reactions are:
  • Olefin metathesis
  • Pd-catalyzed cross coupling reactions including Heck, Suzuki-Miyaura, Sonogashira and Buchwald-Hartwig reactions
  • C-H activation reactions

Second generation amphiphile for cross-coupling reactions in water

Other Notes

Watch Professor Lipshutz talk about TPGS-750-M in this webinar:
From milligrams to kilograms: synthetic chemistry following nature′s lead

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This Item
763896763918900811
form

liquid

form

powder

form

liquid

form

powder or solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

reaction suitability

reagent type: catalyst
reaction type: Bucherer Carbazole Synthesis, reagent type: surfactant

reaction suitability

reagent type: catalyst
reaction type: C-H Activation, reagent type: surfactant

reaction suitability

reagent type: catalyst
reaction type: C-H Activation, reagent type: surfactant

reaction suitability

reagent type: catalyst
reaction type: Asymmetric synthesis

density

1.002 g/mL at 25 °C

density

-

density

0.981 g/mL at 25 °C

density

-

concentration

2 wt. % in H2O

concentration

-

concentration

5 wt. % in H2O

concentration

-

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.


Still not finding the right product?


Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Protocols

TPGS-750-M surfactant enables various reactions in water at room temperature, enhancing efficiency and versatility in synthesis.

Articles

Surfactants for efficient reactions in water as a green chemistry alternative.

A variety of palladium-catalyzed cross-coupling reactions can be run under room temperature conditions in water with TPGS- 750-M, using a variety of commercially available palladium complexes and ligands.

Lipshutz and co-workers have recently developed a second generation technology to their original PTS-enabling surfactant based on the polyoxyethanyl-α-tocopheryl succinate derivative, TPGS-750-M.

Related Content

Designer surfactants enable diverse transformations like Suzuki-Miyaura, Olefin Metathesis, and 1,4-Addition to Enones in water by Prof. Bruce Lipshutz.

Instructions

Amidine-based Catalysts; Advancing Sustainable Catalysis with Magnetite





Global Trade Item Number

SKUGTIN
733857-50ML04061832867571
733857-100ML04061838069993
733857-1.5ML-KC04061838232717
733857-1L04061842293049
733857-10ML04061838085160
733857-500ML04061838098764

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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