Leptophos

Name: Leptophos
Brand: SIAL
Price: 691 PLN

PESTANAL^®, analytical standard

Synonym(s):

O-(4-Bromo-2,5-dichlorophenyl) O-methyl phenylphosphonothioate

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100 MG

PLN 691.00

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About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₀BrCl₂O₂PS

CAS Number:

21609-90-5

Molecular Weight:

412.07

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329754497

EC Number:

244-472-8

Beilstein/REAXYS Number:

2152663

MDL number:

MFCD00128037

Key Documents

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grade

analytical standard

product line

PESTANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, NMR: suitable, gas chromatography (GC): suitable

mp

71-73 °C

suitability

passes test for identity (NMR)

application(s)

agriculture
environmental

format

neat

storage temp.

2-8°C

SMILES string

COP(=S)(Oc1cc(Cl)c(Br)cc1Cl)c2ccccc2

InChI

1S/C13H10BrCl2O2PS/c1-17-19(20,9-5-3-2-4-6-9)18-13-8-11(15)10(14)7-12(13)16/h2-8H,1H3

InChI key

CVRALZAYCYJELZ-UHFFFAOYSA-N

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Analytical Chemistry

Pesticide Standards

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Show Differences

1 of 4

This Item	CRM43602	36126	46279
Supelco 33366 Leptophos	Supelco CRM43602 Leptophos	Supelco 36126 Chlorthiophos	Supelco 46279 Cyanophos
format neat	format -	format neat	format neat
technique(s) HPLC: suitable, gas chromatography (GC): suitable, NMR: suitable	technique(s) -	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable
grade analytical standard	grade certified reference material, TraceCERT^®	grade analytical standard	grade analytical standard
product line PESTANAL^®	product line TraceCERT^®	product line PESTANAL^®	product line PESTANAL^®
shelf life limited shelf life, expiry date on the label	shelf life limited shelf life, expiry date on the label	shelf life limited shelf life, expiry date on the label	shelf life limited shelf life, expiry date on the label
mp 71-73 °C	mp -	mp -	mp -

General description

Leptophos, an organophosphorus insecticide found to be persistent in the environment, shows neurotoxic effects in humans. Its mode of action for pest control involves the inhibition of acetylcholinesterase enzyme activity.

Application

Leptophos may be used as an analytical reference standard for the quantification of the analyte in vegetables using solid phase micro-extraction coupled with gas chromatography-flame photometric detector (SPME-GC-FPD).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS06,GHS08,GHS09

signalword

Danger

hcodes

H300,H311,H370,H410

pcodes

P260 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P312

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - STOT SE 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

flash_point_f

>212.0 °F

flash_point_c

> 100 °C

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Determination of organophosphorus pesticide residues in vegetables using solid phase micro-extraction coupled with gas chromatography-flame photometric detector.

Sapahin AH, et al.

Arabian Journal of Chemistry, 23(1), 636-641 (2014)

Effect of phenobarbital on the delayed neurotoxicity of leptophos in hens.

N Konno et al.

Archives of environmental contamination and toxicology, 15(6), 653-659 (1986-11-01)

Effects of fenthion, fenitrothion and desbromoleptophos on gait, acetylcholinesterase, and neurotoxic esterase in young chicks after in ovo exposure.

M Farage-Elawar et al.

Toxicology, 49(2-3), 253-261 (1988-05-01)

Previous studies have demonstrated that gait is affected in chicks exposed to organophosphorus esters (OPs) that induce delayed neurotoxicity (OPIDN) in adult hens. To investigate the developmental relationship between such functional deficits and OPIDN, chicks were exposed to 3 OPs

Oxidative desulfuration of chlorpyrifos, chlorpyrifos-methyl, and leptophos by rat brain and liver.

J E Chambers et al.

Journal of biochemical toxicology, 4(3), 201-203 (1989-01-01)

The oxidative desulfuration of the three phosphorothionate insecticides--chlorpyrifos, chlorpyrifos-methyl, and leptophos--was studied in rat brain and liver. Hepatic microsomes demonstrated activities of 4-28 nmol/g/min, with male activity 2- to 4-fold higher than female activity. Very low desulfuration activity of all

[Effect of the organophosphorus compounds leptophos and TOCP on creatine kinase activity in hens].

K Katoh et al.

Nihon eiseigaku zasshi. Japanese journal of hygiene, 42(4), 847-857 (1987-10-01)

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