This product is an enzymatically digested fragment of intact plasma fibronectin. This preparation contains the CS-1 heparin-binding region of fibronectin. The 40K fragment is derived from the amino terminal heparin binding portion of the molecule. This fragment has not been sequenced in-house. Therefore, unfortunately more details is unavailable on this line. Please see UniProt Number P02751 for additional information on the sequence and molecular weight.
F1903
Fibronectin 40 kDa α Chymotryptic Fragment (Heparin-binding region), Human purified
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Size/SKU | Availability | Price |
|---|---|---|
500 μg | Estimated to ship on30 September 2026fromKuehne + Nagel Sp. z o.o. | 2.180,00 PLN |
About This Item
UNSPSC Code:
12352202
NACRES:
NA.75
eCl@ss:
32160405
Biological source:
human
Form:
lyophilized
Technique(s):
cell culture | mammalian: suitable
Concentration:
1 mg/mL
Mol wt:
40 kDa
2.180,00 PLN
Estimated to ship on30 September 2026Details
biological source
human
Quality Segment
form
lyophilized
mol wt
40 kDa
manufacturer/tradename
Chemicon®
concentration
1 mg/mL
technique(s)
cell culture | mammalian: suitable
input
sample type epithelial cells
sample type: human embryonic stem cell(s)
sample type mesenchymal stem cell(s)
sample type hematopoietic stem cell(s)
sample type pancreatic stem cell(s)
sample type induced pluripotent stem cell(s)
sample type neural stem cell(s)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... FN1(2335)
General description
Heparin-binding 40 kDa fragment of human plasma fibronectin purified from chymotryptic digest of human plasma fibronectin. This preparation contains the CS-1 heparin-binding region of fibronectin. Heparin-binding fragment promotes cytoskeleton organization in integrin signaling. This preparation shows one major band at 40 kDa in SDS-PAGE with no higher molecular weight species present. Smaller proteolytic fragments may be present.
Human sourced raw material used in the production of this product tested negative for hepatitis B virus, hepatitis C virus (HCV), human immunodeficiency virus type-1 (HIV-1) and type-2 (HIV-2), human T-cell lymphotropic virus (HTLV-1 and HTLV-2) and Treponema pallidum. Handle as if potentially infectious.
Human sourced raw material used in the production of this product tested negative for hepatitis B virus, hepatitis C virus (HCV), human immunodeficiency virus type-1 (HIV-1) and type-2 (HIV-2), human T-cell lymphotropic virus (HTLV-1 and HTLV-2) and Treponema pallidum. Handle as if potentially infectious.
Product Source: Human
Application
ELISA
Affinity chromatography
Possibly for molecular mapping of fibronectin function
Cell attachment and integrin signaling assays
Optimal working dilutions must be determined by the end user.
Affinity chromatography
Possibly for molecular mapping of fibronectin function
Cell attachment and integrin signaling assays
Optimal working dilutions must be determined by the end user.
Physical form
Purified by gelatin-Sepharose and heparin-Sepharose column chromatography. Lyophilized from sodium citrate buffered saline, 20mM, NaCl 150mM, pH 7.4. Reconstitute with distilled water.
Preparation Note
Maintain lyophilized material at -20°C for up to one year from date of receipt. After reconstitution, maintain at -20°C for up to six months in undiluted aliquots. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
1 of 1
This Item | |||
|---|---|---|---|
| description - | description - | description lyophilized powder, BioReagent, suitable for cell culture | description recombinant, expressed in HEK 293 cells, lyophilized powder, suitable for cell culture |
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable |
| biological source human | biological source human | biological source human plasma | biological source human |
| concentration 1 mg/mL | concentration 1 mg/mL | concentration >1 mg/mL protein | concentration - |
| Quality Level 100 | Quality Level 100 | Quality Level 200 | Quality Level 200 |
| mol wt 40 kDa | mol wt 120 kDa | mol wt 450 kDa | mol wt 259.5 kDa (The protein migrates as a higher band on SDS-PAGE due to glycosylation.) |
| form lyophilized | form lyophilized | form lyophilized powder | form lyophilized powder |
Storage Class
11 - Combustible Solids
WGK
WGK 1
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
-
Hi, I would like to know why the fragment is 40KDa if the heparin-binding-site described in UniProt is 25 KDa.
1 answer-
Helpful?
-