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Anti-phospho ULK1 Antibody (Ser777)

Name: Anti-phospho ULK1 Antibody (Ser777)
Brand: MM
Price: 2060 PLN
Availability: InStock

from rabbit, purified by affinity chromatography

Synonym(s):

Serine/threonine-protein kinase ULK1, Serine/threonine-protein kinase Unc51.1, Unc-51-like kinase 1

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Pack Size	SKU	Availability	Price
100 μg		Estimated to ship onMay 26, 2026fromKuehne + Nagel Sp. z o.o.	PLN 2,060.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Clone:

polyclonal

Species reactivity:

human

Application:

WB, inhibition assay

Citations:

PLN 2,060.00

Estimated to ship onMay 26, 2026Details

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Properties

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

inhibition assay: suitable (peptide), western blot: suitable

NCBI accession no.

NP_033495

UniProt accession no.

O70405

shipped in

wet ice

target post-translational modification

phosphorylation (pSer777)

Description

General description

ULK1 or autophagy-related protein 1 homolog (ATG1) is a serine/threonine protein kinase. It is a ubiquitously expressed protein that is highly abundant in the brain, skeletal muscle, and heart. It is involved in the signaling pathway of mTOR receptors leading to the regulation of autophagy in nutrient-deprived cells. mTOR may interact with ULK1 as a complex of ULK1/FIP200/Atg13. ULK1 may play an important role in neuronal development: Elimination of ULK1′s enzymatic activity by targeted disruption of its kinase domain has blocked the outgrowth of neurons in the developing mouse brain, possibly by blocking the ULK1-mediated trafficking of neurotrophins.

~120 kDa observed

Immunogen

KLH-conjugated linear peptide corresponding to a region near the C-terminus of human ULK1 phosphorylated at Ser777.

Application

Anti-phospho ULK1 Antibody (Ser777) is a highly specific rabbit polyclonal antibody, that targets Autophagy-related protein & has been tested in western blotting & Peptide Inhibition Assay.

Evaluated by Western Blotting/Peptide Inhibition Analysis in A431 cell lysate.

Western Blotting/Peptide Inhibition Analysis: 2 µg/mL of this antibody detected phospho ULK1 (Ser777) in 10 µg of A431 cell lysate.

Analysis Note

Evaluated by Western Blotting in A431 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected phospho ULK1 (Ser777) in 10 µg of A431 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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This Item	ABC124	ABC112	SAB1306610
Sigma-Aldrich ABC213 Anti-phospho ULK1 Antibody (Ser777)	Sigma-Aldrich ABC124 Anti-phospho-ULK1 (Ser555) Antibody	Sigma-Aldrich ABC112 Anti-phospho-ULK1/ATG1 (Ser758) Antibody	$ANTI-APG1 (ULK1) (CENTER) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich SAB1306610 ANTI-APG1 (ULK1) (CENTER) antibody produced in rabbit
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level -
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form IgG fraction of antiserum
shipped in wet ice	shipped in wet ice	shipped in wet ice	shipped in wet ice
technique(s) inhibition assay: suitable (peptide), western blot: suitable	technique(s) inhibition assay: suitable (peptide), western blot: suitable	technique(s) inhibition assay: suitable (peptide), western blot: suitable	technique(s) immunofluorescence: 1:100, western blot: 1:1000
species reactivity human	species reactivity human	species reactivity human	species reactivity human

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Porcine epidemic diarrhoea virus (PEDV) infection activates AMPK and JNK through TAK1 to induce autophagy and enhance virus replication.

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Virulence, 13(1), 1697-1712 (2022-09-29)

Autophagy plays an important role in defending against invading microbes. However, numerous viruses can subvert autophagy to benefit their replication. Porcine epidemic diarrhoea virus (PEDV) is an aetiological agent that causes severe porcine epidemic diarrhoea. How PEDV infection regulates autophagy

Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling.

Hyowon Choi et al.

Autophagy, 12(9), 1631-1646 (2016-06-18)

Nucleus pulposus (NP) cells reside in the avascular and hypoxic microenvironment of intervertebral discs. Importantly, many activities related to survival and function of NP cells are controlled by the HIF-family of transcription factors. We hypothesize that NP cells adapt to

UBE3A deficiency-induced autophagy is associated with activation of AMPK-ULK1 and p53 pathways.

Xiaoning Hao et al.

Experimental neurology, 363, 114358-114358 (2023-02-28)

Angelman Syndrome (AS) is a neurodevelopmental disorder caused by deficiency of the maternally expressed UBE3A gene. The UBE3A proteins functions both as an E3 ligase in the ubiquitin-proteasome system (UPS), and as a transcriptional co-activator for steroid hormone receptors. Here

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Global Trade Item Number

SKU	GTIN
ABC213	04053252941191

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