764213

Biotin-PEG4-alkyne

for copper catalyzed click labeling

• Synonym(s): Polyethylene glycol, Acetylene-PEG4-biotin conjugate
• Empirical Formula (Hill Notation): C₂₁H₃₅N₃O₆S
• CAS Number: 1262681-31-1
• Molecular Weight: 457.58
• MDL number: MFCD32689639
• UNSPSC Code: 12161502
• PubChem Substance ID: 329767107
• NACRES: NA.22

Properties

• Assay: 95%
• form: solid
• reaction suitability: reaction type: click chemistry
• mp: 55-64 °C
• storage temp.: −20°C
• SMILES string: O=C(NCCOCCOCCOCCOCC#C)CCCC[C@@H](SC1)[C@@]2([H])[C@]1([H])NC(N2)=O
• InChI: 1S/C21H35N3O6S/c1-2-8-27-10-12-29-14-15-30-13-11-28-9-7-22-19(25)6-4-3-5-18-20-17(16-31-18)23-21(26)24-20/h1,17-18,20H,3-16H2,(H,22,25)(H2,23,24,26)/t17-,18-,20-/m1/s1
• InChI key: SKMJWNZZFUDLKQ-QWFCFKBJSA-N

Description

Application

Biotin-PEG4-alkyne may be used for the modification of 4-azidophenylalanine (AzPhe) silk fibroin via bioorthogonal azide–alkyne cycloaddition reaction for developing photopatternable protein material.[1]

Biotinylation reagent for labeling azide containing molecules or biomolecules using copper-catalyzed 1,3 dipolar cycloaddition click chemistry. The alkyne group reacts with azides to form a stable triazole linkage, facilitating the introduction of biotin into your azide modified system of interest.

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

Other Notes

Chemoproteomic Profiling of Gut Microbiota-Associated Bile Salt Hydrolase Activity

Fluorescent Heterotelechelic Single-Chain Polymer Nanoparticles: Synthesis, Spectroscopy, and Cellular Imaging

Arginine-Selective Chemical Labeling Approach for Identification and Enrichment of Reactive Arginine Residues in Proteins

Selective Imaging of Gram-Negative and Gram-Positive Microbiotas in the Mouse Gut

Metabolic Oligosaccharide Engineering with Alkyne Sialic Acids Confers Neuraminidase Resistance and Inhibits Influenza Reproduction

A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable