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Key Documents

S5758

Sigma-Aldrich

Sodium tetrathionate dihydrate

≥98% (titration)

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About This Item

Linear Formula:
NaO3SS2SO3Na · 2H2O
CAS Number:
Molecular Weight:
306.27
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.26

Assay

≥98% (titration)

solubility

H2O: 200 + 4mL H2O mg, clear to hazy, colorless to faintly yellow

density

2.1 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

O.O.[Na+].[Na+].[O-]S(=O)(=O)SSS([O-])(=O)=O

InChI

1S/2Na.H2O6S4.2H2O/c;;1-9(2,3)7-8-10(4,5)6;;/h;;(H,1,2,3)(H,4,5,6);2*1H2/q2*+1;;;/p-2

InChI key

HAEPBEMBOAIUPN-UHFFFAOYSA-L

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Application


  • Gaussia princeps luciferase: a bioluminescent substrate for oxidative protein folding.: Sodium tetrathionate dihydrate is used to study its impact on the oxidative folding of proteins, utilizing Gaussia princeps luciferase as a bioluminescent substrate. This study advances understanding of protein chemistry and bioluminescence applications in biochemical assays (Yu T et al., 2018).

  • https://doi.org/10.2174/092986612800190973
    https://doi.org/10.1080/10826068.2011.544230
    https://doi.org/10.11150/kansenshogakuzasshi.83.380
  • A spectroscopic investigation into the reaction of sodium tetrathionate with cysteine.: The research utilizes spectroscopic methods to study the reaction between sodium tetrathionate dihydrate and cysteine, providing insights into the chemical interactions and potential applications in biochemistry and molecular biology (Church JS et al., 2008).

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Lars Ole Simonsen et al.
Blood cells, molecules & diseases, 47(4), 214-225 (2011-10-04)
The passive transport of calcium and cobalt and their interference were studied in human red cells using (45)Ca and (57)Co as tracers. In ATP-depleted cells, with the ATP concentration reduced to about 1μM, the progress curve for (45)Ca uptake at
Carlos R Llerena-Suster et al.
Preparative biochemistry & biotechnology, 41(2), 107-121 (2011-03-29)
Papain from latex of Carica papaya was purified up to matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry homogeneity by salt precipitation from two different crude extract sources: a refined preparation obtained in our laboratory and a commercial one. Sodium
Sebastian E Winter et al.
Nature, 467(7314), 426-429 (2010-09-25)
Salmonella enterica serotype Typhimurium (S. Typhimurium) causes acute gut inflammation by using its virulence factors to invade the intestinal epithelium and survive in mucosal macrophages. The inflammatory response enhances the transmission success of S. Typhimurium by promoting its outgrowth in
Bomba Dam et al.
Research in microbiology, 158(4), 330-338 (2007-05-19)
Chemolithotrophic oxidation of reduced sulfur compounds was studied in the betaproteobacterium Tetrathiobacter kashmirensis in correlation with its transposon (Tn5-mob)-inserted mutants impaired in sulfur oxidation (Sox(-)) and found to be carried out via the tetrathionate intermediate (S(4)I) pathway. The group of
Mei Kikumoto et al.
Applied and environmental microbiology, 79(1), 113-120 (2012-10-16)
Thiosulfate dehydrogenase is known to play a significant role in thiosulfate oxidation in the acidophilic, obligately chemolithoautotroph, Acidithiobacillus ferrooxidans. Enzyme activity measured using ferricyanide as the electron acceptor was detected in cell extracts of A. ferrooxidans ATCC 23270 grown on

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