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M5266

Sigma-Aldrich

Meglumine diatrizoate

organic

Sinónimos:

N-Methyl-D-glucamine diatrizoate

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About This Item

Fórmula empírica (notación de Hill):
C7H17NO5 · C11H9I3N2O4
Número de CAS:
131-49-7
Peso molecular:
809.13
EC Number:
205-024-7
MDL number:
MFCD00069632
UNSPSC Code:
12352201
PubChem Substance ID:
24896990
NACRES:
NA.25

biological source

synthetic (organic)

Quality Level

200

form

powder

optical activity

[α]25/D -6.4 to -5.7 °, c = 1% (w/v) in water

SMILES string

CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C(O)=O)c1I

InChI

1S/C11H9I3N2O4.C7H17NO5/c1-3(17)15-9-6(12)5(11(19)20)7(13)10(8(9)14)16-4(2)18;1-8-2-4(10)6(12)7(13)5(11)3-9/h1-2H3,(H,15,17)(H,16,18)(H,19,20);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1

InChI key

MIKKOBKEXMRYFQ-WZTVWXICSA-N

General description

Meglumine Diatrizoate is an organic, iodinated meglumine salt form of diatrizoate. It is also known as N-Methyl-D-glucamine diatrizoate.

Application

Meglumine diatrizoate can be used to treat long-term Taenia saginata infection. It has also been used to tag fecal matter and bodily fluids in a study investigating preoperative examination techniques in patients with acute colon obstruction caused by colorectal cancer.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Shoji Hirasaki et al.
Internal medicine (Tokyo, Japan), 51(2), 177-179 (2012-01-17)
A 46-year-old Japanese man visited our hospital for chronic abdominal pain, persistent diarrhea and discharge of proglottids for 7 years. He had been living in Lao People's Democratic Republic. Ileography using meglumine/diatrizoate sodium (Gastrografin) revealed a long tapeworm. A Taenia
Cheng Tien Wu et al.
Toxicology and applied pharmacology, 266(1), 167-175 (2012-11-03)
Contrast medium (CM) induces a direct toxic effect on renal tubular cells. This toxic effect subjects in the disorder of CM-induced nephropathy. Our previous work has demonstrated that CM shows to activate the endoplasmic reticulum (ER)-related adaptive unfolding protein response
Patrick Veit-Haibach et al.
European radiology, 23(1), 163-173 (2012-07-10)
Computed tomography perfusion (CTP) can provide information about angiogenesis and blood-flow characteristics in tumours. [18F]Fluoro-2-deoxy-D-glucose-positron emission tomography/computed tomography (FDG-PET/CT) is one of the major oncological imaging techniques which provides information about viability of the tumour cell and partly also about
Nicolas C Buchs et al.
Swiss medical weekly, 142, w13556-w13556 (2012-04-07)
In most centers, Upper Gastrointestinal series (UGI) following Roux-en-Y Gastric Bypass (RYGB) is performed to rule out GJ anastomotic leak. According to the introduction of robotic technology associated with a hypothetical decrease of anastomotic complications, we aim to assess the
B Dustin Pooler et al.
Radiology, 268(1), 127-134 (2013-03-02)
To assess the variation in diagnostic performance among radiologists at screening computed tomographic (CT) colonography. In this HIPAA-compliant, institutional review board-approved study, 6866 asymptomatic adults underwent first-time CT colonographic screening at a single center between January 2005 and November 2011.
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