L8134
Linoleic acid sodium salt
≥97% (GC)
Sinónimos:
Sodium linolate, Sodium linoleate, cis-9,cis-12-Octadecadienoic acid sodium salt
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About This Item
Fórmula lineal:
C18H31O2Na
Número de CAS:
Peso molecular:
302.43
Número CE:
Número MDL:
Código UNSPSC:
12352211
ID de la sustancia en PubChem:
NACRES:
NA.25
Productos recomendados
origen biológico
plant oil (safflower)
Nivel de calidad
Ensayo
≥97% (GC)
Formulario
powder
técnicas
activity assay: suitable
color
white
mp
230 °C (446 °F)
solubilidad
methanol: 50 mg/mL, clear, yellow
aplicaciones
general analytical
life science and biopharma
grupo funcional
carboxylic acid
tipo de lípido
omega FAs
Condiciones de envío
ambient
temp. de almacenamiento
−20°C
cadena SMILES
[Na+].CCCCC\C=C/C\C=C/CCCCCCCC([O-])=O
InChI
1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b7-6-,10-9-;
Clave InChI
WYPBVHPKMJYUEO-NBTZWHCOSA-M
Descripción general
Linoleic acid, an essential omega-6 polyunsaturated fatty acid (PUFA), serves as a precursor to arachidonic acid (AA), necessary for synthesizing prostaglandins and other eicosanoids. Being an essential fatty acid, linoleic acid must be acquired through diet as the body cannot produce it. Deficiencies in linoleic acid are linked to health issues such as impaired wound healing, growth retardation, and dermatitis. Arachidonate 15 Lipoxygenase (15-LO) metabolizes linoleic acid in both plants and animals, forming 9- and 13-hydroxyoctadecadienoic acid (HODE). This versatile molecule finds applications in biochemical, metabolomics, and lipidomics research, enabling investigations into various metabolic pathways and providing insights into lipid functions in living organisms.
Aplicación
Linoleic acid sodium salt has been used:
- in the β-carotene-linoleic acid assay
- as a component in basal medium to treat peripheral blood mononuclear cells (PBMCs)
- in Dulbecco′s modified Eagle′s medium (DMEM)/F-12 HEPES (4-(2-hydroxyethyl) piperazine-1-ethanesulfonic acid) to incubate human trophoblast-derived choriocarcinoma cells (BeWo) and study its effects on adherens junctions (AJ) marker level, cell layer permeability, and intracellular lipid accumulation
Acciones bioquímicas o fisiológicas
Linoleic acid, as a component of acylglycosyl ceramides, plays a physiological role in maintaining the water permeability barrier of the skin. The deficiency of linoleic acid may cause poor growth or development, scaly dermatitis, and an impaired immune response in infants. It is used in cosmetic and personal care products. Linoleic acid is mainly used as emollients or moisturizers for skin, nails, and hair.
Características y beneficios
- High-quality molecule suitable for mulitple research applications
- Commonly employed in Metabolomics and Biochemical studies
Otras notas
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Palabra de señalización
Warning
Frases de peligro
Clasificaciones de peligro
Skin Irrit. 2
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
dust mask type N95 (US), Eyeshields, Gloves
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