It is soluble in 50 mM ammonium hydroxide at a concentration of 1 mg/mL. Note that this is information from analytical testing, and is not application based.
C9026
Caerulein
≥95% (HPLC), suitable for immunohistochemistry
Sinónimos:
Caerulein Sulfated, Cerulein, Ceruletide, [Tyr(SO3H)4]Caerulein, pGlu-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2
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About This Item
Fórmula empírica (notación de Hill):
C58H73N13O21S2
Número de CAS:
Peso molecular:
1352.40
Beilstein:
5422487
Número MDL:
Código UNSPSC:
12352209
ID de la sustancia en PubChem:
NACRES:
NA.26
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Nombre del producto
Caerulein, ≥95% (HPLC)
Nivel de calidad
Ensayo
≥95% (HPLC)
Formulario
powder
técnicas
immunohistochemistry: suitable
color
white
temp. de almacenamiento
−20°C
cadena SMILES
CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)C(NC(=O)[C@H](Cc3ccc(OS(O)(=O)=O)cc3)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]4CCC(=O)N4)[C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc5ccccc5)C(N)=O
InChI
1S/C58H73N13O21S2/c1-29(72)49(71-57(87)40(23-31-12-14-33(15-13-31)92-94(89,90)91)68-56(86)43(26-48(78)79)69-52(82)37(16-18-44(59)73)65-51(81)36-17-19-45(74)63-36)58(88)62-28-46(75)64-41(24-32-27-61-35-11-7-6-10-34(32)35)54(84)66-38(20-21-93-2)53(83)70-42(25-47(76)77)55(85)67-39(50(60)80)22-30-8-4-3-5-9-30/h3-15,27,29,36-43,49,61,72H,16-26,28H2,1-2H3,(H2,59,73)(H2,60,80)(H,62,88)(H,63,74)(H,64,75)(H,65,81)(H,66,84)(H,67,85)(H,68,86)(H,69,82)(H,70,83)(H,71,87)(H,76,77)(H,78,79)(H,89,90,91)/t29-,36+,37+,38+,39+,40+,41+,42+,43+,49?/m1/s1
Clave InChI
YRALAIOMGQZKOW-HJMGKOKZSA-N
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Categorías relacionadas
Amino Acid Sequence
Glp-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2
Aplicación
Acciones bioquímicas o fisiológicas
Caerulein is a gastro regulatory molecule with actions similar to cholecystokinin.[4] It possesses a tyrosine sulfate residue and induces smooth muscle contraction. It has gastrin-like activity.[5] Caerulein is used to study cell signaling mediated by NF-κB upregulation of proteins such as intercellular adhesion molecule-1(ICAM-1) and inflammation related molecules, such as NADPH oxidase and Janus kinase signal transducer.[6] Caerulein also regulates thermoregulation, sedation and satiety.[5]
Effects on perception of pain are conflicting. It prevents gall bladder pain, renal colic, and the pain of intermittent claudication; however, in general, it is seen as an antagonist of endogenous opioids.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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What is Product C9026, Caerulein, soluble in?
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How do I store solutions of Product C9026, Caerulein?
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Solutions can be frozen at pH>7 for a least a week, and may be good for several months.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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