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A4979

Sigma-Aldrich

Anti-Water Channel Aquaporin 5 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Sinónimos:

Anti-AQP-5, Anti-PPKB

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About This Item

MDL number:
MFCD02262548
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse, rat

technique(s)

western blot: 1:200-1:500 using mouse salivary gland and rat lung

UniProt accession no.

Q9WTY4

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

mouse ... Aqp5(11830)
rat ... Aqp5(25241)

General description

Anti-Water Channel Aquaporin 5 binds to aquaporin 5 from mouse salivary gland and rat lung membranes.
Aquaporin-5 is part of a family of aquaporins that function to transport water across cell membranes. AQP5 is involved in tear, saliva, and sweat production.
Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0).

Immunogen

peptide corresponding to residues 251-265 of rat AQP5. The sequence is identical in mouse and 10/16 residues identical in human.

Application

Rabbit Anti-Water Channel Aquaporin 5 antibody can be used for western blot at a dilution of 1:200-1:500 using mouse salivary gland and rat lung tissue extracts.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, 1% BSA, ≤0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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J W Snuggs et al.
Scientific reports, 11(1), 3164-3164 (2021-02-06)
The central region of the intervertebral disc (IVD) is rich in proteoglycans, leading to a hyperosmotic environment, which fluctuates with daily loading. The cells of the nucleus pulposus (NP cells) have adapted to this environment via the function of tonicity
Michael G Haase et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 62(5), 355-368 (2014-03-29)
Ionizing radiation (IR) leads to fibrosing alveolitis (FA) after a lag period of several weeks to months. In a rat model, FA starts at 8 weeks after IR. Before that, at 5.5 weeks after IR, the transcription factors Sp1 (stimulating
Mulugu V Brahmajothi et al.
Antioxidants & redox signaling, 21(13), 1823-1836 (2014-08-05)
The aims of this study were to determine hyperoxia effects on S-nitrosothiol (SNO) accumulation and L-type amino acid transporter 1 (LAT1) expression/function in alveolar epithelium and to determine whether hyperoxia impairs exogenous nitric oxide (NO) treatment effects in alveolar epithelium
Hongyu Wu et al.
PloS one, 8(1), e53342-e53342 (2013-01-18)
Dot1l encodes histone H3 K79 methyltransferase Dot1a. Mice with Dot1l deficiency in renal Aqp2-expressing cells (Dot1l(AC)) develop polyuria by unknown mechanisms. Here, we report that Aqp5 links Dot1l deletion to polyuria through Aqp2. cDNA array analysis revealed and real-time RT-qPCR
Christina Vohlen et al.
Cells, 10(11) (2021-11-28)
Prematurely born infants often require supplemental oxygen that impairs lung growth and results in arrest of alveolarization and bronchopulmonary dysplasia (BPD). The growth hormone (GH)- and insulin-like growth factor (IGF)1 systems regulate cell homeostasis and organ development. Since IGF1 is
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