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Y0000509

Desogestrel

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

13-Ethyl-11-methylene-18,19-dinor-17α-4-pregnen-20-yn-17-ol

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About This Item

Fórmula empírica (notación de Hill):
C22H30O
Número de CAS:
54024-22-5
Peso molecular:
310.47
Número MDL:
MFCD00869346
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329830992
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

desogestrel

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

CC[C@]12CC(=C)[C@H]3[C@@H](CCC4=CCCC[C@H]34)[C@@H]1CC[C@@]2(O)C#C

InChI

1S/C22H30O/c1-4-21-14-15(3)20-17-9-7-6-8-16(17)10-11-18(20)19(21)12-13-22(21,23)5-2/h2,8,17-20,23H,3-4,6-7,9-14H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1

Clave InChI

RPLCPCMSCLEKRS-BPIQYHPVSA-N

Información sobre el gen

human ... PGR(5241)

Categorías relacionadas

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Desogestrel EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Cláusula de descargo de responsabilidad

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Y0000510

Desogestrel, European Pharmacopoeia (EP) Reference Standard

1173268

Etonogestrel, United States Pharmacopeia (USP) Reference Standard

1173235

Desogestrel, United States Pharmacopeia (USP) Reference Standard

1173257

Desogestrel Related Compound B, United States Pharmacopeia (USP) Reference Standard

1173246

Desogestrel Related Compound A, United States Pharmacopeia (USP) Reference Standard

1173279

Desogestrel Related Compound D, United States Pharmacopeia (USP) Reference Standard

BP816

Etonogestrel, British Pharmacopoeia (BP) Reference Standard

BP817

Desogestrel impurity E, British Pharmacopoeia (BP) Reference Standard

Pictogramas

Health hazardEnvironment
GHS08,GHS09

Palabra de señalización

Danger

Frases de peligro

H360FD,H410

Clasificaciones de peligro

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

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K Fotherby
Contraception, 51(1), 3-12 (1995-01-01)
The clinical experience with a combined oral contraceptive (COC) containing 150 micrograms desogestrel and 30 micrograms ethinylestradiol is reviewed. Fourteen clinical trials have been reported involving over 44,000 women for more than 190,000 cycles. None of the 17 pregnancies which
H D McClamrock et al.
American journal of obstetrics and gynecology, 168(3 Pt 2), 1021-1028 (1993-03-01)
A synthetic form of desogestrel, a gonane progestin, was developed because desogestrel's enhanced selectivity eliminates adverse, androgen-dependent, metabolic effects at contraceptive doses. Desogestrel is rapidly and completely metabolized in the liver and gut wall to 3-keto-desogestrel, which is the active
R T Burkman
American journal of obstetrics and gynecology, 168(3 Pt 2), 1033-1040 (1993-03-01)
Desogestrel is a gonane progestogen that in early studies had an improved ratio between desired progestational effects and undesired androgenic effects. A review of more than 50 clinical studies suggests that desogestrel differs from progestins currently used in oral contraception
L Laurendeau
Canadian family physician Medecin de famille canadien, 42, 62-71 (1996-01-01)
A review of clinical trials of changes in lipoprotein composition in women receiving oral contraceptives containing desogestrel; a comparison of the trials' findings and a discussion of their clinical significance. Using MEDLINE, we searched for articles published in English and
P G Stubblefield
American journal of obstetrics and gynecology, 168(3 Pt 2), 1047-1052 (1993-03-01)
Epidemiologic research has shown that current low-dose estrogen oral contraceptives are associated with a low risk of vascular events (e.g., myocardial infarction, stroke, and venous thrombosis or thromboembolism). Yet questions still persist about the effects of low-dose oral contraceptives on
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