PHR1061

Valproic acid

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: 2-Propylpentanoic acid, 2-Propylvaleric acid, Valproic acid
• Fórmula lineal: (CH₃CH₂CH₂)₂CHCO₂H
• Número de CAS: 99-66-1
• Peso molecular: 144.21
• Número CE: 202-777-3
• Número MDL: MFCD00002672
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329823091
• NACRES: NA.24

Propiedades

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to Ph. Eur. V0033000; traceable to USP 1708707
• familia API: valproic acid
• CofA: current certificate can be downloaded
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• índice de refracción: n20/D 1.425 (lit.)
• bp: 220 °C (lit.)
• densidad: 0.9 g/mL at 25 °C (lit.)
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• temp. de almacenamiento: 2-30°C
• cadena SMILES: CCCC(C(O)=O)CCC
• InChI: 1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
• Clave InChI: NIJJYAXOARWZEE-UHFFFAOYSA-N
• Información sobre el gen: human ... ALDH5A1(7915)

Descripción

Descripción general

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

It is widely used in the treatment of bipolar disorder, migraine, depression, epilepsy and schizophrenia.

Valproic acid is a branched short chain fatty acid, which finds applications as a antiepileptic drug.

Aplicación

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Valproic acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using gas chromatography technique.

Acciones bioquímicas o fisiológicas

Anticonvulsant that also has efficacy as a mood stabilizer in bipolar disorder

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAB3712 in the slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Información de seguridad

• Pictogramas: GHS08,GHS05,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H302,H315,H318,H360FD
• Consejos de prudencia: P202 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1A - Skin Irrit. 2
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 231.8 °F - closed cup
• Punto de inflamabilidad (°C): 111 °C - closed cup