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Merck

P5631

Sigma-Aldrich

o-Cresolphthalein Complexone

powder

Sinónimos:

o-Cresolphthalein-3′,3′′-bis-methyleneiminodiacetic acid, o-Cresolphthalexon, Metal phthalein, Phthalein purple, Xylenylphthalein-bisiminodiacetic acid

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About This Item

Fórmula empírica (notación de Hill):
C32H32N2O12
Número de CAS:
Peso molecular:
636.60
Beilstein:
381994
Número CE:
Número MDL:
Código UNSPSC:
12171500
ID de la sustancia en PubChem:
NACRES:
NA.47

Formulario

powder

Nivel de calidad

técnicas

titration: suitable

color

white to off-white

mp

181-185 °C (dec.) (lit.)

solubilidad

methanol: 1 mg/mL

idoneidad

suitable for determination of calcium

aplicaciones

diagnostic assay manufacturing
hematology
histology

temp. de almacenamiento

room temp

cadena SMILES

Cc1cc(cc(CN(CC(O)=O)CC(O)=O)c1O)C2(OC(=O)c3ccccc23)c4cc(C)c(O)c(CN(CC(O)=O)CC(O)=O)c4

InChI

1S/C32H32N2O12/c1-17-7-21(9-19(29(17)43)11-33(13-25(35)36)14-26(37)38)32(24-6-4-3-5-23(24)31(45)46-32)22-8-18(2)30(44)20(10-22)12-34(15-27(39)40)16-28(41)42/h3-10,43-44H,11-16H2,1-2H3,(H,35,36)(H,37,38)(H,39,40)(H,41,42)

Clave InChI

IYZPEGVSBUNMBE-UHFFFAOYSA-N

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Descripción general

o-Cresolphthalein Complexone is a pH indicator dye commonly used for the calorimetric determination of calcium in serum.

Aplicación

o-Cresolphthalein Complexone has been used in the estimation of calcium in serum samples based on the reaction of Ca2+ with o-cresolphthalein complexone in an alkaline solution.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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C M Corns et al.
Annals of clinical biochemistry, 24 ( Pt 4), 345-351 (1987-07-01)
The reasons for the non-linearity of the standard curve for the calcium-cresolphthalein complexone reaction have been investigated. Calcium forms both 1:1 and 2:1 complexes with cresolphthalein complexone; at low calcium concentrations the 1:1 complex predominates and causes non-linearity. At high
J Toffaletti et al.
Clinical chemistry, 26(11), 1562-1565 (1980-10-01)
We adapted a method for dialyzable calcium from fluorometric detection by use of calcein to a more specific spectrophotometric determination with cresolphthalein complexone. The reagents are available commercially and perform satisfactorily with respect to noise level, drift, stability, and sensitivity.
M A Koupparis et al.
Clinical chemistry, 28(10), 2149-2152 (1982-10-01)
We describe the measurement of total calcium and magnesium in serum with an automated microcomputer-controlled stopped-flow analyzer. The calcium method is based on the cresolphthalein complexone procedure, with 2-amino-3-methyl-1-propanol as the alkalinizing agent. The assay, performed on 60-fold prediluted samples
R J Liedtke et al.
Clinical chemistry, 27(12), 2025-2028 (1981-12-01)
We describe an automated method for calcium assay, for use with the Cobas-Bio centrifugal analyzer. Calcium is reacted with cresolphthalein complexone and the absorbance of the calcium--dye complex at 575 nm is measured. EDTA is then added to break up
B Aghabeigi et al.
International journal of oral and maxillofacial surgery, 31(6), 646-649 (2003-01-11)
Saline aspirates have been commonly used in the biochemical investigations of temporomandibular joint (TMJ) pathology. However, due to presence of adhesions in the diseased temporomandibular joint, full equilibration between the injected saline and the synovial fluid may not be achieved

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