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C85778

Sigma-Aldrich

o-Cresolphthalein

Indicator grade, powder

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About This Item

Fórmula empírica (notación de Hill):
C22H18O4
Número de CAS:
596-27-0
Peso molecular:
346.38
Beilstein:
310554
Número CE:
209-881-8
Número MDL:
MFCD00005912
Código UNSPSC:
12171500
ID de la sustancia en PubChem:
24893078
NACRES:
NA.47

Nombre del producto

o-Cresolphthalein, indicator grade

grado

indicator grade

Nivel de calidad

200

Formulario

powder

técnicas

titration: suitable

color

beige

pH

8.2-9.8, colorless to red

mp

219-221 °C (lit.)

λmáx.

381 nm (2nd)
566 nm

ε (coeficiente de extinción)

≥10000 at 294-300 nm
≥39000 at 564-570 nm
≥5000 at 378-384 nm

aplicaciones

diagnostic assay manufacturing
hematology
histology

temp. de almacenamiento

room temp

cadena SMILES

Cc1cc(ccc1O)C2(OC(=O)c3ccccc23)c4ccc(O)c(C)c4

InChI

1S/C22H18O4/c1-13-11-15(7-9-19(13)23)22(16-8-10-20(24)14(2)12-16)18-6-4-3-5-17(18)21(25)26-22/h3-12,23-24H,1-2H3

Clave InChI

CPBJMKMKNCRKQB-UHFFFAOYSA-N

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Aplicación

O-Cresolphthalein has been used as a component in calcifying media for calcification assay.

Acciones bioquímicas o fisiológicas

o-Cresolphthalein is a reversible pH indicator. The kinetics of the reverse pathway (red-purple to colorless) is slow, thereby making it an appropriate molecule to check flow patterns in ducts with corrugated walls. It is also used for the colorimetric determination of calcium content via the o-cresolphthalein complexone method. Binding of calcium to o-cresolphthalein, in the presence of alkaline conditions (pH 10-12), results in the formation of a red complex with an absorbance at 570-575nm.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
SHBS3612
SHBR5596
SHBR0493
MKCK2964
MKCG9431

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Natalia Campos-Obando et al.
European journal of epidemiology (2018-05-17)
Hyperphosphatemia has been associated with increased mortality in chronic kidney disease but the nature of such a relation in the general population is unclear. To investigate the association between phosphate (P) levels and all-cause and cause-specific mortality, we assessed two
Jin-Hyun Kim et al.
PloS one, 14(4), e0215244-e0215244 (2019-04-17)
In the stratum corneum, the intercellular junction made up of cadherin proteins provides the structural integrity of the framework. Ca2+ ions are known to play a key role in maintaining this junction. In this study, we hypothesized that Ca2+ chelation
Hyunseok Peter Kang et al.
Clinical chemistry, 50(4), 741-746 (2004-02-14)
Gadolinium formulations, which are administered as contrast agents in magnetic resonance imaging examinations, interfere with colorimetric serum calcium determinations. We performed an in vitro study to determine the extent to which three gadolinium formulations-gadodiamide (Omniscan), gadopentetate dimeglumine (Magnevist), and gadoversetamide
Ali Duran et al.
Journal of hazardous materials, 169(1-3), 466-471 (2009-04-29)
In present study preconcentration followed by solid phase extraction of heavy metal ions, Cu(II), Co(II), Ni(II) and Pb(II) using a multiwalled carbon nanotubes (MWNTs) and complexing reagent o-cresolphthalein complexone were investigated. The effects of parameters, including pH of the solutions
Alon Abend et al.
EMBO reports, 18(7), 1166-1185 (2017-06-08)
A pathologic osteochondrogenic differentiation of vascular smooth muscle cells (VSMCs) promotes arterial calcifications, a process associated with significant morbidity and mortality. The molecular pathways promoting this pathology are not completely understood. We studied VSMCs, mouse aortic rings, and human aortic
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