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D2950000

Disulfiram

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Tetraethylthiuram disulfide, Bis(diethylthiocarbamoyl) disulfide, Bis(diethylthiocarbamyl) disulfide, Disulfiram, TETD

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About This Item

Fórmula lineal:
(C2H5)2NCSS2CSN(C2H5)2
Número de CAS:
97-77-8
Peso molecular:
296.54
Beilstein:
1712560
Número CE:
202-607-8
Número MDL:
MFCD00009048
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329798762
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

disulfiram

fabricante / nombre comercial

EDQM

mp

69-71 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

cadena SMILES

CCN(CC)C(=S)SSC(=S)N(CC)CC

InChI

1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3

Clave InChI

AUZONCFQVSMFAP-UHFFFAOYSA-N

Información sobre el gen

human ... ALDH2(217)

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Alcohol dehydrogenase inhibitor.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Palabra de señalización

Warning

Frases de peligro

H302,H317,H373,H410

Clasificaciones de peligro

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1 - STOT RE 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Daidzin ≥95.0% (HPLC)

Sigma-Aldrich

30408

Daidzin

SAHA ≥98% (HPLC)

Sigma-Aldrich

SML0061

SAHA

Sodium diethyldithiocarbamate trihydrate ACS reagent

Sigma-Aldrich

228680

Sodium diethyldithiocarbamate trihydrate

Charlotte H Jørgensen et al.
Alcoholism, clinical and experimental research, 35(10), 1749-1758 (2011-05-28)
Alcohol use disorders (AUD) involving hazardous, harmful, and addictive misuse of alcohol are widespread in most parts of the world. The aim of this study was to review the effect of disulfiram in the treatment of patients with AUD. The
Pier Paolo Pani et al.
The Cochrane database of systematic reviews, (1)(1), CD007024-CD007024 (2010-01-22)
Cocaine dependence is a disorder for which no pharmacological treatment of proven efficacy exists, advances in the neurobiology could guide future medication development. To evaluate the efficacy and the acceptability of disulfiram for cocaine dependence. We searched: PubMed, EMBASE, CINAHL
Boris Cvek et al.
Drug discovery today, 13(15-16), 716-722 (2008-06-27)
The major approach to the development of anticancer drugs involves searching for new compounds, efficient against malignancies, which are not, as yet, used clinically. This strategy is time-consuming and expensive. Recent studies have disclosed a surprising, but mechanistically consistent, anticancer
Joanna Triscott et al.
Oncotarget, 3(10), 1112-1123 (2012-10-11)
Glioblastomas (GBM) are associated with high rates of relapse. These brain tumors are often resistant to chemotherapies like temozolomide (TMZ) and there are very few treatment options available to patients. We recently reported that polo-like kinase-1 (PLK1) is associated with
Martin Loss et al.
Transplantation, 95(9), 1134-1141 (2013-02-26)
The majority of pancreases, offered in allocation, are discarded. This pancreas underutilization is not well understood yet. We analyzed the detailed allocation protocols of all Eurotransplant-registered German whole-pancreas donors (2005-2009; n=1758). Outcome measures included donor characteristics, number of refusals per
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