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Merck
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36-002

Sigma-Aldrich

Anti-phospho-SGK Antibody

serum, Upstate®

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
En este momento no podemos mostrarle ni los precios ni la disponibilidad

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

serum

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

human

fabricante / nombre comercial

Upstate®

técnicas

western blot: suitable

isotipo

IgG

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

phosphorylation (pSer422/pThr256)

Información sobre el gen

human ... SGK1(6446)

Especificidad

Recognizes phospho-SGK.

Inmunógeno

peptide corresponding to amino acids surrounding Ser255/Thr256 of human SGK1.

Aplicación

Anti-phospho-SGK Antibody is an antibody against phospho-SGK for use in WB.
Not recommended for use with cell lysates.
Research Category
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling

Calidad

routinely evaluated by immunoblot detected phospho-SGK after phosphorylation of unactive SGK1 (Catalog # 14-332) with PDK1 (Catalog # 14-280)

Descripción de destino

48 kDa

Forma física

UnPurified whole rabbit antiSerum containing 30% glycerol and 0.035% sodium azide.
Unpurified

Almacenamiento y estabilidad

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Nota de análisis

Control
PDK activated SGK samples

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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J Park et al.
The EMBO journal, 18(11), 3024-3033 (1999-06-05)
Serum and glucocorticoid-inducible kinase (SGK) is a novel member of the serine/threonine protein kinase family that is transcriptionally regulated. In this study, we have investigated the regulatory mechanisms that control SGK activity. We have established a peptide kinase assay for
Jian-Bang Xu et al.
Signal transduction and targeted therapy, 9(1), 74-74 (2024-03-26)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection disrupts the epithelial barrier and triggers airway inflammation. The envelope (E) protein, a core virulence structural component of coronaviruses, may play a role in this process. Pathogens could interfere with transepithelial Cl-
Yi-Lin Zhang et al.
Mucosal immunology, 11(4), 1149-1157 (2018-03-17)
Airway epithelial cells harbor the capacity of active Cl- transepithelial transport and play critical roles in modulating innate immunity. However, whether intracellular Cl- accumulation contributes to relentless airway inflammation remains largely unclear. This study showed that, in airway epithelial cells
Joseph R Shaw et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 22(1-4), 69-78 (2008-09-05)
Killifish are euryhaline teleosts that adapt to increased salinity by up regulating CFTR mediated Cl(-) secretion in the gill and opercular membrane. Although many studies have examined the mechanisms responsible for long term (days) adaptation to increased salinity, little is
Phase II trial of temsirolimus in patients with metastatic breast cancer.
Gini F Fleming,Cynthia X Ma,Dezheng Huo,Husain Sattar,Maria Tretiakova,L Lin,Olwen M Hahn et al.
Breast Cancer Research and Treatment null

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