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Merck

725986

Sigma-Aldrich

Trimethylsilanol

≥97.5% (GC)

Sinónimos:

TMS, TMSiOH, Hydroxytrimethylsilane

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About This Item

Fórmula lineal:
(CH3)3SiOH
Número de CAS:
Peso molecular:
90.20
Beilstein/REAXYS Number:
1361356
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.22

assay

≥97.5% (GC)

form

liquid

SMILES string

C[Si](C)(C)O

InChI

1S/C3H10OSi/c1-5(2,3)4/h4H,1-3H3

InChI key

AAPLIUHOKVUFCC-UHFFFAOYSA-N

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Application

Trimethylsilanol (TMS) can be used to prepare tris(trimethylsiloxy) aluminum (I) by reacting with triethylaluminum.

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

44.6 °F - closed cup

flash_point_c

7 °C - closed cup


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During the past years, there has been an increasing focus on the presence of silicone oil as a contaminant in pharmaceutical formulations kept in prefilled syringes (PFSs). As the PFSs are coated on the inner wall with silicone oil (polydimethylsiloxane)
Reactions of Aldehyde Caused by Tris (trimethylsiloxy) aluminum.
Saegusa T, et al.
Bulletin of the Chemical Society of Japan, 40(8), 1960-1964 (1967)
Xiao-Meng Chong et al.
Drug development and industrial pharmacy, 45(1), 159-167 (2018-09-21)
Establish an effective experimental strategy to determine the compatibility of rubber closures for drugs. Various types of rubber closures with different compositions are available for drug packaging. Many additives of rubber closures can be released from rubber closures and may
Paul T J Scheepers et al.
Journal of occupational medicine and toxicology (London, England), 12, 33-33 (2017-12-14)
In most reported cases of lung trauma with water proofing products, volatile organic compounds (VOC) have a prominent role. Here we report on a case involving ten workers exposed to a sprayed product containing nanoparticles in a water solution with
Diane M Coe et al.
Organic & biomolecular chemistry, 1(7), 1106-1111 (2003-08-21)
A convenient and efficient method for the cleavage of 1,3-oxazolidin-5-ones and 1,3-oxazolidin-2-ones utilising potassium trimethylsilanolate in tetrahydrofuran is described. The benzyloxycarbonyl-protecting group is readily removed under the reaction conditions, whereas the N-benzoyl group is stable. A synthesis of (R)-salmeterol exploiting

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