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Sigma-Aldrich

1H-1,2,3-Triazole

97%

Sinónimos:

2,3-Diazapyrrole, 2H-1,2,3-Triazole, Osotriazole, Pyrrodiazole, Triazacyclopentadiene

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About This Item

Fórmula empírica (notación de Hill):
C2H3N3
Número de CAS:
288-36-8
Peso molecular:
69.07
Número MDL:
MFCD00014490
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
24860165
NACRES:
NA.22
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Ensayo

97%

Formulario

liquid

índice de refracción

n20/D 1.498 (lit.)

bp

203 °C/752 mmHg (lit.)

mp

23-25 °C (lit.)

densidad

1.192 g/mL at 25 °C (lit.)

cadena SMILES

c1c[nH]nn1

InChI

1S/C2H3N3/c1-2-4-5-3-1/h1-2H,(H,3,4,5)

Clave InChI

QWENRTYMTSOGBR-UHFFFAOYSA-N

Categorías relacionadas

Descripción general

2H-1,2,3-triazole is tautomeric form of 1H-1,2,3-triazole. 1H-1,2,3-triazole effectively promotes the proton conduction in polymer electrolyte membranes via an intermolecular proton-transfer mechanism.[1]

Aplicación

  • Crystalline framework materials: Research on triazole carboxylic acid ligand has demonstrated its application in smart crystalline framework materials, notably for fluorescence sensing and catalytic reduction of p-nitrophenol, illustrating its utility in chemical sensing and environmental applications (Lv et al., 2023).
  • PXR receptor modulation: 1H-1,2,3-Triazole-4-carboxamides have been optimized as potent and selective inverse agonists and antagonists of the PXR receptor, providing insights into the design of receptor-specific drugs (Li et al., 2022).
  • Large-scale synthesis: The large-scale synthesis of a Notum inhibitor employing a modified Sakai reaction illustrates the importance of 1H-1,2,3-triazole in the production of biochemical reagents, which can be essential in medical research and drug development (Atkinson et al., 2022).

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H315,H319,H335

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

224.6 °F - closed cup

Punto de inflamabilidad (°C)

107 °C - closed cup

Equipo de protección personal

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificados de análisis (COA)

Lot/Batch Number
STBL3118
STBL2887
STBK6164
STBJ3105
STBJ3103

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Kashif Mahmood et al.
International journal of molecular sciences, 20(24) (2019-12-11)
NAC (NAM (no apical meristem), ATAF1/2, and CUC2 (cup-shaped cotyledon)) proteins are one of the largest families of plant-specific transcription factors, and this family is present in a wide range of land plants. Here, we have investigated the role of
Paco Pino et al.
PLoS pathogens, 3(8), e115-e115 (2007-09-06)
Toxoplasma gondii is an aerobic protozoan parasite that possesses mitochondrial antioxidant enzymes to safely dispose of oxygen radicals generated by cellular respiration and metabolism. As with most Apicomplexans, it also harbors a chloroplast-like organelle, the apicoplast, which hosts various biosynthetic
Bertrand Boson et al.
PLoS pathogens, 7(7), e1002144-e1002144 (2011-08-05)
Hepatitis C virus (HCV) assembly remains a poorly understood process. Lipid droplets (LDs) are thought to act as platforms for the assembly of viral components. The JFH1 HCV strain replicates and assembles in association with LD-associated membranes, around which viral
Atul Bhardwaj et al.
Nature communications, 8(1), 1-1 (2017-02-25)
Cyclooxygenase-2 isozyme is a promising anti-inflammatory drug target, and overexpression of this enzyme is also associated with several cancers and neurodegenerative diseases. The amino-acid sequence and structural similarity between inducible cyclooxygenase-2 and housekeeping cyclooxygenase-1 isoforms present a significant challenge to
Fong-Fong Chu et al.
World journal of gastroenterology, 22(46), 10158-10165 (2016-12-29)
To test whether Nox1 plays a role in typhlitis induced by Salmonella enterica serovar Typhimurium (S. Tm) in a mouse model. Eight-week-old male wild-type (WT) and Nox1 knockout (KO) C57BL6/J (B6) mice were administered metronidazole water for 4 d to
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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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