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Merck

1044516

USP

Atorvastatin Calcium

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Atorvastatin hemicalcium salt sesquihydrate

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About This Item

Fórmula empírica (notación de Hill):
C66H68CaF2N4O10 · 3H2O
Número de CAS:
Peso molecular:
1209.39
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

atorvastatin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/2C33H35FN2O5.Ca.3H2O/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;;;;/h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);;3*1H2/q;;+2;;;/p-2/t2*26-,27-;;;;/m11..../s1

InChI key

SHZPNDRIDUBNMH-NIJVSVLQSA-L

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Atorvastatin Calcium is a synthetic selective inhibitor of HMG-CoA reductase. It is insoluble in aqueous solution with pH below 4 and is freely soluble in methanol.

Application

Atorvastatin calcium USP reference standard intended for use in specified quality tests and assays.

Also used to prepare system suitability, standard, system suitability stock, identification, and standard stock solution for assay and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Atorvastatin Calcium
  • Atorvastatin Calcium Tablets
  • Amlodipine and Atorvastatin Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Carc. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Atorvastatin Calcium
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 35(1), 414-414 (2022)
Development and validation of analytical methods for simultaneous estimation of atorvastatin calcium and ezetimibe in combined dosage form.
Rajamanickam, V., et al.
World Applied Sciences Journal , 9.12, 1424-1429 (2010)
Atorvastatin and Atorvastatin Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(2), 265-265 (2020)
Atorvastatin Calcium Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(1), 418-418 (2020)
Xiao-ling Li et al.
International immunopharmacology, 23(2), 546-549 (2014-12-03)
This study aimed to investigate the efficacy of combined atorvastatin calcium and methylprednisolone for the treatment of multiple sclerosis relapse. Patients with multiple sclerosis (MS) at the relapse phase were randomized to receive either combined treatment of atorvastatin calcium and

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