1021204

4-Aminophenol

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: 4-Hydroxyaniline
• Fórmula lineal: H₂NC₆H₄OH
• Número de CAS: 123-30-8
• Peso molecular: 109.13
• Beilstein/REAXYS Number: 385836
• MDL number: MFCD00007869
• UNSPSC Code: 41116107
• PubChem Substance ID: 329748983
• NACRES: NA.24

Propiedades

• grade: pharmaceutical primary standard
• API family: paracetamol, acetaminophen, mesalazine
• manufacturer/tradename: USP
• mp: 185-189 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: Nc1ccc(O)cc1
• InChI: 1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
• InChI key: PLIKAWJENQZMHA-UHFFFAOYSA-N

Descripción

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.4-Aminophenol is the principal degradation product of acetaminophen, formed as an impurity during its hydrolysis.

Application

This USP reference standard is intended for use in specified quality tests and assays.
Also used to prepare standard and system suitability solutions to test for the presence of 4-aminophenol as an impurity in various pharmaceutical dosage forms of acetaminophen, according to the United States Pharmacopeia (USP) monographs:

• Mesalamine
• Acetaminophen Tablets
• Acetaminophen Oral Suspension
• Tramadol Hydrochloride and Acetaminophen Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Información de seguridad

• pictograms: GHS08,GHS07,GHS09
• signalword: Warning
• hcodes: H302 + H332,H317,H341,H373,H410
• pcodes: P273 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Skin Sens. 1 - STOT RE 2
• target_organs: Kidney
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable