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Merck

S5393

Sigma-Aldrich

Serum minus IgA/IgM/IgG human

lyophilized powder

Sinónimos:

Depleted Serum

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.46

origen biológico

human

Nivel de calidad

conjugado

unconjugated

Formulario

lyophilized powder

contiene

15 mM sodium azide

envase

vial of 0.5 mL

temp. de almacenamiento

2-8°C

modificación del objetivo postraduccional

unmodified

Descripción general

Serum is the liquid component of blood that includes proteins, immunoglobulin and electrolytes. The product can be used for selective removal of contaminating antibodies when immobilized on a solid matrix. This product can also be used in anti-protective antigen (anti-PA) IgG measurements using PA coupled microspheres. Human serum deficient of IgG, IgA, and IgM can react specifically with anti-human whole serum but does not show reactivity with anti-human IgG, IgA, or IgM.

Aplicación

Serum minus IgA/IgM/IgG human has been used as a control serum in immunoelectrophoresis, immunodiffusion,enzyme linked immunosorbent assay. It has also been used as
  • control sera to assess neuraminidase inhibition
  • microneutralization assay
  • single radial hemolysis (SRH) repeatability assay

Cantidad

Each vial contains at least 25 mg protein

Reconstitución

Reconstitute with 0.5 mL deionized water.

Cláusula de descargo de responsabilidad

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Raymond E Biagini et al.
Clinical and diagnostic laboratory immunology, 10(5), 744-750 (2003-09-11)
We describe a fluorescent covalent microsphere immunoassay (FCMIA) method for the simultaneous (multiplexed) measurement of immunoglobulin G (IgG) antibodies to 23 pneumococcal capsular polysaccharide (PnPS) serotypes present in the pneumococcal polysaccharide vaccine (PPV23) licensed by the Food and Drug Administration
Thorunn A Olafsdottir et al.
Frontiers in immunology, 8, 1872-1872 (2018-01-24)
Influenza vaccination remains the best strategy for the prevention of influenza virus-related disease and reduction of disease severity and mortality. However, there is large individual variation in influenza vaccine responses. In this study, we investigated the effects of gender, age
Karina Jawinski et al.
Frontiers in immunology, 10, 2661-2661 (2019-12-05)
Current influenza vaccines manufactured using eggs have considerable limitations, both in terms of scale up production and the potential impact passaging through eggs can have on the antigenicity of the vaccine virus strains. Alternative methods of manufacture are required, particularly
Fabrizio Biuso et al.
Influenza and other respiratory viruses, 13(5), 504-516 (2019-08-15)
Formulation of neuraminidase (NA) within influenza vaccines is gaining importance in light of recent human studies. The enzyme-linked lectin assay (ELLA) is considered a reliable assay to evaluate human anti-NA antibodies. To overcome interference by hemagglutinin (HA)-specific antibodies and detect
Age and influenza-specific pre-vaccination antibodies strongly affect influenza vaccine responses in the Icelandic population whereas disease and medication have small effects
Olafsdottir TA, et al.
Frontiers in Immunology, 8, 1872-1872 (2018)

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