Ethanol is commonly used as a solvent for reconstitution of this product for cell culture applications. Although solubility in ethanol is not a tested specification for batch release, this product is known to dissolve in ethanol up to a concentration of 20 mg/mL. Sonication is not necessary for reconstitution in ethanol.
O1383
Ácido oleico
BioReagent, suitable for cell culture
Sinónimos:
Ácido cis-9-octadecenoico, Ácido elaínico
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About This Item
Fórmula lineal:
CH3(CH2)7CH=CH(CH2)7COOH
Número de CAS:
Peso molecular:
282.46
Beilstein:
1726542
Número CE:
Número MDL:
Código UNSPSC:
12352211
ID de la sustancia en PubChem:
NACRES:
NA.75
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Productos recomendados
origen biológico
palm oil
Nivel de calidad
presión de vapor
1 mmHg ( 176 °C)
Línea del producto
BioReagent
Ensayo
≥99% (GC)
Formulario
viscous liquid
técnicas
cell culture | mammalian: suitable
índice de refracción
n20/D 1.459 (lit.)
bp
194-195 °C/1.2 mmHg (lit.)
mp
13-14 °C (lit.)
solubilidad
ethanol: soluble
densidad
0.89 g/mL at 25 °C (lit.)
0.89 g/mL at 25 °C (lit.)
temp. de almacenamiento
−20°C
cadena SMILES
CCCCCCCC\C=C/CCCCCCCC(O)=O
InChI
1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
Clave InChI
ZQPPMHVWECSIRJ-KTKRTIGZSA-N
Información sobre el gen
human ... SOAT1(6646) , SOAT2(8435)
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Categorías relacionadas
Descripción general
Oleic acid is a mono-unsaturated omega-9 fatty acid created by dehydrogenation of stearic acid. It is then further dehydrogenated and elongated to create members of the n-9 family of fatty acids. Oleic acid is not an essential fatty acid (EFA); however, providing it to cells in culture reduces energy demand.
Oleic acid mediates complete oxidation of fatty acid in sirtuin1- proliferator-activated receptor γ coactivator−1α (SIRT1-PGC-1α) signalling pathway. Oleic acid shows anti-inflammatory properties related to atherosclerosis and insulin resistant state.[1] Oleic acid inhibits permeability in gap junctions and promotes glucose uptake in astrocytes. Oleic acid aids in neural cell proliferation by increasing glucose uptake and by protein kinase C (PKC) activation. Oleic acid is essential for axonal growth and neuronal clustering.[2]
Aplicación
Envase
Sealed ampule.
Precaución
Unsaturated fatty acids are subject to oxidation and peroxidation. Consider complexed fatty acid supplements.
Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 1
Equipo de protección personal
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Elija entre una de las versiones más recientes:
Certificados de análisis (COA)
Lot/Batch Number
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Los clientes también vieron
Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1alpha complex
Lim JH, et al.
The Journal of Biological Chemistry, 288(10), 7117-7126 (2013)
The role of proliferator-activated receptor gamma coactivator-1alpha in the fatty-acid-dependent transcriptional control of interleukin-10 in hepatic cells of rodents
Morari J, et al.
Metabolism, Clinical and Experimental, 59(2), 215-223 (2010)
Beneficial effect of fish oil on human brain (2009)
Three-dimensional label-free imaging and quantification of lipid droplets in live hepatocytes
Kim K, et al.
Scientific Reports, 6(10), 36815-36815 (2016)
Stefan Freigang et al.
Nature immunology, 14(10), 1045-1053 (2013-09-03)
Chronic inflammation is a fundamental aspect of metabolic disorders such as obesity, diabetes and cardiovascular disease. Cholesterol crystals are metabolic signals that trigger sterile inflammation in atherosclerosis, presumably by activating inflammasomes for IL-1β production. We found here that atherogenesis was
Artículos
Lipid Induced Insulin Resistance
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Hello. I would like to know if it is necessary to sonicate the oleic acid before stimulation? what is the best solvent? Thank you!
1 answer-
Helpful?
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What is the concentration of this oleic acid and what solvent do I need to make dilution
1 answer-
This product is a neat or pure liquid and has not been diluted. This material has a density of 0.890 g/mL and a molecular weight of 282.46 g/mol. The minimum purity is 99%, thus the molarity will vary slightly from lot to lot. The molarity can range from 3.12 M (99%) to 3.15 M (100%).
Helpful?
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What is the concentration of this product-O1383-25G?
1 answer-
The concentration of this product can be determined using the lot-specific purity reported in the Certificate of Analysis, as well as the density and compound molecular weight. This product has a density of 0.89 g/mL and a molecular weight of 282.46 g/mol. The minimum purity is 99%, thus the molarity will vary slightly from lot to lot. The molarity can range from 3.12 M (99%) to 3.15 M (100%).
Helpful?
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Has product O1383-25g been received in a glass container or ampule?
1 answer-
Based on the packaging information, product O1383-25g has been received in a glass ampule.
Helpful?
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