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M6013

Sigma-Aldrich

Medroxyprogesterone

Sinónimos:

17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione, 17α-Hydroxy-6α-methylprogesterone, 6α-Methyl-5-pregnen-17α-ol-3,20-dione, 6-Dihydromegestrol

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About This Item

Fórmula empírica (notación de Hill):
C22H32O3
Número de CAS:
520-85-4
Peso molecular:
344.49
Beilstein/REAXYS Number:
2510965
EC Number:
208-298-6
MDL number:
MFCD00069474
UNSPSC Code:
51111800
PubChem Substance ID:
24897065
NACRES:
NA.77

biological source

synthetic (organic)

assay

≥98% (HPLC)

form

powder

solubility

chloroform: 50 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(C)=O

InChI

1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1

InChI key

FRQMUZJSZHZSGN-HBNHAYAOSA-N

Gene Information

rat ... Ar(24208)

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Caution

Much of the pharmacology literature refers to medroxyprogesterone acetate as medroxyprogesterone, but they are of course not the same substance.

related product

Referencia del producto
Descripción
Precios

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H361fd

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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The role of medroxyprogesterone acetate (MPA) in the treatment of renal adenocarcinoma.
M Kjaer
Cancer treatment reviews, 15(3), 195-209 (1988-09-01)
James Hassell et al.
Hormones and behavior, 60(2), 219-225 (2011-06-04)
Progestins and antiprogestins are widely used therapeutic agents in humans. In many cases, these are indicated for the treatment of reproductive activities. However, progesterone has widespread physiological effects including a reduction of the response to stress. We have reported that
Kevin D Beck et al.
Neurobiology of learning and memory, 97(1), 148-155 (2011-12-06)
Ovarian hormones modulate acquisition processes involved in classical conditioning. Although progesterone has been indirectly implicated, its role in classical conditioning of the eyeblink response has not been directly investigated. We assessed the effects of daily dosing of progesterone or medroxyprogesterone
A Günzel-Apel et al.
Reproduction in domestic animals = Zuchthygiene, 47 Suppl 6, 55-60 (2013-01-04)
Progesterone profiles of individual bitches may vary considerably both between and within individuals during pregnancy and non-pregnancy. Suspected luteal deficiency is commonly purported but is difficult to evaluate in clinical cases when progesterone is supplemented because this masks the underlying
P C Schwallie
Contraception, 23(4), 375-386 (1981-04-01)
Data from published studies of the quantity of medroxyprogesterone acetate and/or its metabolites in the milk of lactating women receiving Depo-Provera for contraception is extrapolated into the amount of drug ingested daily by a theoretically average infant. Comparisons are made
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