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Merck

M5639

Sigma-Aldrich

4-Methylumbelliferyl β-D-N,N′,N′′-triacetylchitotrioside

glycanase substrate, fluorogenic, ≥98.00% (TLC), powder

Sinónimos:

4-Methyl-7-coumarinyl-tri-N-acetyl-β-chitotrioside, 4-Methylumbelliferyl-N,N′,N″-triacetyl-β-chitotrioside

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About This Item

Fórmula empírica (notación de Hill):
C34H47N3O18
Número de CAS:
Peso molecular:
785.75
Beilstein:
5710839
Número MDL:
Código UNSPSC:
12352204
ID de la sustancia en PubChem:
NACRES:
NA.32

Nombre del producto

4-Methylumbelliferyl β-D-N,N′,N′′-triacetylchitotrioside, fluorogenic glycanase substrate

Nivel de calidad

Ensayo

≥98.00% (TLC)

Formulario

powder

solubilidad

water: pyridine, 1:1: 4.90-5.10 mg/mL, clear, colorless to light yellow

temp. de almacenamiento

2-8°C

cadena SMILES

CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]2[C@H](O)[C@@H](NC(C)=O)[C@@H](O[C@@H]2CO)O[C@H]3[C@H](O)[C@@H](NC(C)=O)[C@@H](O[C@@H]3CO)Oc4ccc5C(C)=CC(=O)Oc5c4

InChI

1S/C34H47N3O18/c1-12-7-22(44)50-18-8-16(5-6-17(12)18)49-32-24(36-14(3)42)28(47)30(20(10-39)52-32)55-34-25(37-15(4)43)29(48)31(21(11-40)53-34)54-33-23(35-13(2)41)27(46)26(45)19(9-38)51-33/h5-8,19-21,23-34,38-40,45-48H,9-11H2,1-4H3,(H,35,41)(H,36,42)(H,37,43)/t19-,20-,21-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33+,34+/m1/s1

Clave InChI

BNYGKUQXGBVTRE-JFWBNMEYSA-N

Aplicación

4-Methylumbelliferyl β-D-N,N′,N′′-triacetylchitotrioside has been used as a fluorogenic substrate to determine chitinase and chitotriosidase enzyme activity.

Sustratos

Fluorogenic substrate for endochitinases, peptidoglycan muramidase, and lysozyme.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Michael B Howard et al.
Journal of bacteriology, 185(11), 3352-3360 (2003-05-20)
The marine bacterium Microbulbifer degradans strain 2-40 produces at least 10 enzyme systems for degrading insoluble complex polysaccharides (ICP). The draft sequence of the 2-40 genome allowed a genome-wide analysis of the chitinolytic system of strain 2-40. The chitinolytic system
M V Telkov et al.
Biochemistry. Biokhimiia, 71(4), 414-422 (2006-04-18)
The secreted Micrococcus luteus protein, Rpf, is required for successful resuscitation of dormant "non-culturable" M. luteus cells and for growth stimulation in poor media. The biochemical mechanism of Rpf action remained unknown. Theoretical predictions of Rpf domain architecture and organization
Sarah Kim et al.
Molecular genetics and metabolism reports, 29, 100803-100803 (2021-10-15)
Elevated serum chitotriosidase (CHITO) is an indication of macrophage activation, and its capacity have been explored as a marker of inflammation in a number of disease states. For over a decade, CHITO plasma levels have been used by clinicians as
Gavriella Mavrikiou et al.
Clinical biochemistry, 49(12), 885-889 (2016-05-01)
The purpose of this study was to determine the normal range of chitotriosidase activity in the Cypriot population and the frequency of the 24bp duplication polymorphism. Furthermore, we compared the allele frequency of this polymorphism in two locations with different
Unnur Dilja Teitsdottir et al.
Sleep & breathing = Schlaf & Atmung, 22(4), 1101-1109 (2018-10-13)
The inflammatory markers chitinase-3-like protein 1 (CHI3L1) and chitotriosidase (CHIT1) have both been associated with cardiovascular complications. The aim of this preliminary observational study was to assess the roles and interaction of obstructive sleep apnea (OSA) severity and body mass

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