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M9130

Sigma-Aldrich

4-Methylumbelliferyl-β-D-glucuronide hydrate

≥98% (HPLC), BioReagent, for identification of transformed plants

Sinónimos:

4-Methylumbelliferyl-β-D-glucopyranosiduronic acid, MUG

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About This Item

Fórmula empírica (notación de Hill):
C16H16O9 · xH2O
Número de CAS:
881005-91-0
Peso molecular:
352.29 (anhydrous basis)
Número MDL:
MFCD09039280
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
329818083
NACRES:
NA.52
En este momento no podemos mostrarle ni los precios ni la disponibilidad

grado

for molecular biology

Nivel de calidad

200

Línea del producto

BioReagent

Ensayo

≥98% (HPLC)

Formulario

powder

solubilidad

pyridine: 50 mg/mL, clear, colorless to very faintly yellow

temp. de almacenamiento

−20°C

cadena SMILES

O.CC1=CC(=O)Oc2cc(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)ccc12

InChI

1S/C16H16O9.H2O/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22;/h2-5,11-14,16,18-20H,1H3,(H,21,22);1H2/t11-,12-,13+,14-,16+;/m0./s1

Clave InChI

URVSQZMOFUEQAW-YYHOVTOASA-N

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Descripción general

MUG is a chemical commonly used for the detection of transformed plants. MUG shows low levels of fluorescence until treatment with glucuronidase (GUS) encoded in transformed plants. Transformed plants can be identified by their MUG fluorescence.

Aplicación

Suitable for fluorescent detection of glucuronidase gene expression in plants.

Reconstitución

Product is soluble in molecular biology grade water at a concentration of 0.35 mg/ml.

Producto relacionado

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000393780
0000374057
0000352631
0000352623
0000352617

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L J Moberg
Applied and environmental microbiology, 50(6), 1383-1387 (1985-12-01)
An assay procedure to screen for Escherichia coli in foods by using 4-methylumbelliferyl-beta-D-glucuronide (MUG) incorporated into lauryl tryptose (LST) broth was evaluated. The beta-glucuronidase produced by E. coli cleaves the MUG substrate to yield a fluorescent end product. E. coli-negative
Andrew G Kunihiro et al.
Molecular nutrition & food research, 64(14), e2000072-e2000072 (2020-06-09)
Curcumin prevents bone loss in resorptive bone diseases and inhibits osteoclast formation, a key process driving bone loss. Curcumin circulates as an inactive glucuronide that can be deconjugated in situ by bone's high β-glucuronidase (GUSB) content, forming the active aglycone.
Yuan Ruan et al.
Current biology : CB, 28(17), 2718-2729 (2018-08-28)
The capacity for sustained cell division within the plant meristem is a critical determinant of organ structure and performance. This capacity is diminished in mutants lacking the microtubule-associated protein CLASP and when brassinosteroid signaling is increased. Here, we discovered that
M C Thaller et al.
Journal of clinical microbiology, 26(4), 791-793 (1988-04-01)
A new selective, differential plating medium to screen the common gram-negative urinary tract pathogens is described. The medium combines adonitol fermentation, phenylalanine deaminase, and beta-glucuronidase tests and allows the indole and cytochrome oxidase tests to be performed directly from the
Helena C Besse et al.
Pharmaceutics, 12(6) (2020-06-14)
The poor pharmacokinetics and selectivity of low-molecular-weight anticancer drugs contribute to the relatively low effectiveness of chemotherapy treatments. To improve the pharmacokinetics and selectivity of these treatments, the combination of a doxorubicin-glucuronide prodrug (DOX-propGA3) nanogel formulation and the liberation of
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