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Key Documents

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G3127

Sigma-Aldrich

Gly-Sar

≥98% (TLC)

Sinónimos:

Glycyl-sarcosine

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About This Item

Fórmula lineal:
NH2CH2CON(CH3)CH2COOH
Número de CAS:
29816-01-1
Peso molecular:
146.14
Beilstein/REAXYS Number:
1768450
EC Number:
249-875-2
MDL number:
MFCD00038193
UNSPSC Code:
12352209
PubChem Substance ID:
24895113
NACRES:
NA.26

product name

Gly-Sar,

assay

≥98% (TLC)

form

powder

color

white

mp

198 °C

storage temp.

−20°C

SMILES string

CN(CC(O)=O)C(=O)CN

InChI

1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10)

InChI key

VYAMLSCELQQRAE-UHFFFAOYSA-N

Gene Information

human ... SLC15A1(6564)

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Hovhannes J Gukasyan et al.
Pharmaceutical research, 34(12), 2488-2497 (2017-08-24)
Studies were conducted in primary cultured rat alveolar epithelial cell monolayers to characterize peptide transporter expression and function. Freshly isolated rat lung alveolar epithelial cells were purified and cultured on permeable support with and without keratinocyte growth factor (KGF). Messenger
Jinling Wang et al.
International journal of nanomedicine, 13, 7997-8012 (2018-12-13)
Polymeric micelles (PMs) hold promise for improving solubility and oral absorption of poorly soluble drugs. Unfortunately, the oral absorption of PMs is also limited by intestinal epithelium. To improve the oral delivery efficiency of micelles, transporter-mediated micelles could enhance the
S Frølund et al.
British journal of pharmacology, 161(3), 589-600 (2010-10-01)
BACKGROUND AND PURPOSE The intestinal proton-coupled amino acid transporter, SLC36A1, transports zwitterionic α-amino acids and drugs such as vigabatrin, gaboxadol and δ-aminolevulinic acid. We hypothesize that SLC36A1 might also transport some dipeptides. The aim of the present study was to
Shuping Li et al.
Frontiers in pharmacology, 8, 541-541 (2017-09-06)
Harmaline and harmine occur naturally in plants and are distributed endogenously in human and animal tissues. The two β-carboline alkaloids possess potential for treating Alzheimer's disease, Parkinson's disease, depression and other central nervous system diseases. However, studies have showed that
Ina Hubatsch et al.
Journal of medicinal chemistry, 50(21), 5238-5242 (2007-09-25)
The hPepT1-mediated transport properties of a series of 11 synthesized beta- and gamma-peptides have been studied in Caco-2 cells. The results show that several of the compounds interact with the peptide transporter, but only two beta-dipeptides act as substrates and
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