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G2878

Sigma-Aldrich

Glycocholic acid hydrate

synthetic, ≥97% (HPLC)

Sinónimos:

3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide, Cholylglycine, N-(3α,7α,12α-Trihydroxy-24-oxocholan-24-yl)-glycine

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About This Item

Fórmula empírica (notación de Hill):
C26H43NO6 · xH2O
Número de CAS:
1192657-83-2
Peso molecular:
465.62 (anhydrous basis)
Beilstein:
2955826
Número MDL:
MFCD06408004
Código UNSPSC:
12161900
ID de la sustancia en PubChem:
24895107
NACRES:
NA.25
En este momento no podemos mostrarle ni los precios ni la disponibilidad

origen biológico

synthetic

Nivel de calidad

200

descripción

anionic

Ensayo

≥97% (HPLC)

Formulario

powder

mol peso

average mol wt 1000

número de agregación

2.1

técnicas

enzyme immunoassay: suitable

CMC

7.1

grupo funcional

amide

Condiciones de envío

ambient

temp. de almacenamiento

room temp

cadena SMILES

O.C[C@H](CCC(=O)NCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C26H43NO6.H2O/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29;/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33);1H2/t14-,15+,16-,17-,18+,19+,20-,21+,24+,25+,26-;/m1./s1

Clave InChI

WDKPRHOCWKLQPK-ZUHYDKSRSA-N

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Aplicación

Glycocholic acid hydrate has been used in a study to assess the invasiveness of Cryptosporidium spp. Into cultured cells. [1] It has also been used in a study to investigate the interaction of chitosan and oil-in-water emulsions under conditions simulating the digestive system. [2]

Acciones bioquímicas o fisiológicas

Bile Acid

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Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Equipo de protección personal

Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000368727
0000368732
0000368727
0000368732
0000273413

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Andre Pascal Kengne et al.
The lancet. Diabetes & endocrinology, 2(1), 19-29 (2014-03-14)
The comparative performance of existing models for prediction of type 2 diabetes across populations has not been investigated. We validated existing non-laboratory-based models and assessed variability in predictive performance in European populations. We selected non-invasive prediction models for incident diabetes
Judith Vandepitte et al.
Sexually transmitted diseases, 41(4), 233-237 (2014-03-14)
Recent antimicrobial resistance data for Neisseria gonorrhoeae are lacking in Uganda, where, until 2010, ciprofloxacin was the nationally recommended first-line treatment of presumptive gonorrhea. This study assessed the antimicrobial susceptibility patterns of N. gonorrhoeae isolates cultured from female sex workers
Hanping Feng et al.
Infection and immunity, 74(6), 3342-3346 (2006-05-23)
Bile salts such as sodium taurocholate (NaTC) are routinely used to induce the excystation of Cryptosporidium oocysts. Here we show that NaTC significantly enhanced the invasion of several cultured cell lines by freshly excysted Cryptosporidium parvum and Cryptosporidium hominis sporozoites.
Emanuel Christ et al.
The lancet. Diabetes & endocrinology, 1(2), 115-122 (2014-03-14)
Small benign insulinomas are hard to localise, leading to difficulties in planning of surgical interventions. We aimed to prospectively assess the insulinoma detection rate of single-photon emission CT in combination with CT (SPECT/CT) with a glucagon-like peptide-1 receptor avid radiotracer
Jacqueline M Major et al.
The Journal of nutrition, 144(5), 729-733 (2014-03-14)
Vitamin E (α-tocopherol) plays a key role in the regulation of cell growth and differentiation and has been studied as a potential chemopreventive agent for prostate cancer. The association of serum vitamin E concentrations with cancer risk may be modified
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Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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