T6260

Sodium taurochenodeoxycholate

• Sinónimos: 2-([3α,7α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid sodium salt, 3α,7α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt, Taurochenodeoxycholic acid sodium salt
• Fórmula empírica (notación de Hill): C₂₆H₄₄NNaO₆S
• Número de CAS: 6009-98-9
• Peso molecular: 521.69
• Beilstein/REAXYS Number: 3901205
• MDL number: MFCD00036745
• UNSPSC Code: 41141802
• PubChem Substance ID: 24900362
• NACRES: NA.25

Propiedades

• description: anionic
• assay: ≥95.0% (TLC)
• form: powder
• mol wt: 521.69 g/mol
• CMC: 4
• HLB: 20.1
• functional group: sulfonic acid
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(NCCS(=O)([O-])=O)=O.[Na+]
• InChI: 1S/C26H45NO6S.Na/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29;/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1/t16-,17+,18-,19-,20+,21+,22-,24?,25+,26-;/m1./s1
• InChI key: IYPNVUSIMGAJFC-ULWOGUKGSA-M

Descripción

General description

An ionic detergent used for solubilizing lipids and proteins.

Sodium taurochenodeoxycholate is a bile acid that can be used as an anionic detergent.

Application

Sodium taurochenodeoxycholate has been used in a study to assess whether pancreatic β-cells contribute to BA-dependent regulation of glucose. It has also been used in a study to investigate short-term feedback regulation of sodium taurocholate cotransporting polypeptide (Ntcp) by bile salts in vivo.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)