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Merck

C0158

Sigma-Aldrich

L-Carnitine inner salt

≥98%

Sinónimos:

(−)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate, Vitamin BT

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About This Item

Fórmula lineal:
(CH3)3N+CH2CH(OH)CH2COO-
Número de CAS:
Peso molecular:
161.20
Beilstein:
4292315
Número CE:
Número MDL:
Código UNSPSC:
12352209
ID de la sustancia en PubChem:
NACRES:
NA.79
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Nombre del producto

L-Carnitine inner salt, synthetic, ≥98%

origen biológico

synthetic

Nivel de calidad

Ensayo

≥98%

Formulario

powder

color

white

mp

197-212 °C (lit.)

aplicaciones

cell analysis
detection

cadena SMILES

C[N+](C)(C)C[C@H](O)CC([O-])=O

InChI

1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1

Clave InChI

PHIQHXFUZVPYII-ZCFIWIBFSA-N

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Aplicación

L-Carnitine inner salt has been used as a component of an assay medium for Seahorse XF mitochondrial stress assay.[1] It has also been orally administered to tumor-bearing mice, in order to study its effect on the regulation of peroxisome proliferator-activated receptor and thereby to analyse liver inflammatory response.[2]

Acciones bioquímicas o fisiológicas

Carnitine biosynthesized from lysine. Carnitine facilitates fatty acid transport into the mitochondrial compartment.[3] In skeletal and cardiac muscle tissue it acts as a metabolic cofactor. Carnitine might be associated with the energy production from branched chain amino acids.[4]
Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves


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Los clientes también vieron

Sunil K Panchal et al.
Food & function, 6(8), 2496-2506 (2015-07-21)
Obesity and dyslipidaemia are metabolic defects resulting from impaired lipid metabolism. These impairments are associated with the development of cardiovascular disease and non-alcoholic fatty liver disease. Correcting the defects in lipid metabolism may attenuate obesity and dyslipidaemia, and reduce cardiovascular
L-carnitine ameliorates the liver inflammatory response by regulating carnitine palmitoyltransferase I-dependent PPAR? signaling
Fang Jiang
Molecular Medicine Reports, 13(2) (2015)
N A Oey et al.
Placenta, 27(8), 841-846 (2005-11-23)
Carnitine plays an indispensable role in fatty acid oxidation. Previous studies revealed that fetal carnitine is derived from the mother via transplacental transfer. Recent studies demonstrated the presence and importance of an active fatty acid oxidation system in the human
Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects.
Ahmad S
Kidney International, 38(5), 912-918 (1990)
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Koeth RA
Nature Medicine, 19(5), 576-585 (2013)

Questions

  1. Hello, After dissolving the product in water, I want to ask about the storage conditions to ensure the stability of the product L-carnitine inner salt, product number C0158.

    1 answer
    1. The solution stability of this product has not been determined. It is recommended to prepare solutions fresh before use.

      Helpful?

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