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S1950000

Sulfadoxina

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

4-amino-N-(5,6-dimetoxi-4-pirimidinil)benzenosulfamida, Sulfadoxina

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About This Item

Fórmula empírica (notación de Hill):
C12H14N4O4S
Número de CAS:
2447-57-6
Peso molecular:
310.33
Beilstein:
625453
Número MDL:
MFCD00792890
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329824497
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

sulfadoxine

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

COc1ncnc(NS(=O)(=O)c2ccc(N)cc2)c1OC

InChI

1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)

Clave InChI

PJSFRIWCGOHTNF-UHFFFAOYSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Sulfadoxine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

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Descripción
Precios

Pictogramas

Exclamation markEnvironment
GHS07,GHS09

Palabra de señalización

Warning

Frases de peligro

H317,H411

Clasificaciones de peligro

Aquatic Chronic 2 - Skin Sens. 1

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

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Certificados de análisis (COA)

Lot/Batch Number

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Alexia Daoust et al.
NeuroImage, 96, 133-142 (2014-04-08)
The MAP6 (microtubule-associated protein 6) KO mouse is a microtubule-deficient model of schizophrenia that exhibits severe behavioral disorders that are associated with synaptic plasticity anomalies. These defects are alleviated not only by neuroleptics, which are the gold standard molecules for
Philip J Peters et al.
Drug safety, 30(6), 481-501 (2007-06-01)
Plasmodium falciparum infection during pregnancy is strongly associated with maternal anaemia and low birth weight, contributing to substantial morbidity and mortality in sub-Saharan Africa. Intermittent preventive treatment in pregnancy with sulfadoxine/pyrimethamine (IPTp-SP) has been one of the most effective approaches
C H Sibley et al.
Trends in parasitology, 17(12), 582-588 (2002-01-05)
Chemotherapy remains the only practicable tool to control falciparum malaria in sub-Saharan Africa, where >90% of the world's burden of malaria mortality and morbidity occurs. Resistance is rapidly eroding the efficacy of chloroquine, and the combination pyrimethamine-sulfadoxine is the most
Sankar Sridaran et al.
The American journal of tropical medicine and hygiene, 90(5), 840-845 (2014-03-13)
Chloroquine (CQ) is used as a first-line therapy for the treatment of Plasmodium falciparum malaria in Nicaragua. We investigated the prevalence of molecular markers associated with CQ and sulfadoxine-pyrimethamine (SP) resistance in P. falciparum isolates obtained from the North Atlantic
H M McIntosh et al.
Annals of tropical medicine and parasitology, 92(3), 265-270 (1998-08-26)
The 4-aminoquinolines, chloroquine or amodiaquine, have long been the drugs of choice for treating uncomplicated, falciparum malaria in Africa, although resistance to them is now common. Sulfadoxine-pyrimethamine (SP) is the usual alternative when 4-aminoquinoline treatment fails. A combination-treatment regimen could
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