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AB5795

Sigma-Aldrich

Anti-Calcium Channel γ 4 Antibody

Chemicon®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human, rat

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_014405.2

UniProt accession no.

Q9UBN1

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... CACNG4(27092)
mouse ... Cacng4(54377)
rat ... Cacng4(140725)

Specificity

gamma4 calcium channel (Voltage-Dependant Calcium Channel, gamma4 subunit).

Immunogen

Synthetic peptide from rat gamma4 calcium channel.

Application

Anti-Calcium Channel Antibody, γ 4 detects level of Calcium Channel & has been published & validated for use in WB.
Immunoblotting: 5-10 μg/mL. Reacts with the 36.5 kD protein.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters

Signaling Neuroscience

Physical form

Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.08% sodium azide.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Analysis Note

Control
Rat brain lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Alterations in AMPA receptor subunits and TARPs in the rat nucleus accumbens related to the formation of Ca??-permeable AMPA receptors during the incubation of cocaine craving.
Ferrario, CR; Loweth, JA; Milovanovic, M; Ford, KA; Gali?anes, GL; Heng, LJ; Tseng, KY; Wolf, ME
Neuropharmacology null
Balakrishnan Selvakumar et al.
Neuropharmacology, 77, 28-38 (2013-09-17)
Behavioral sensitization to cocaine is associated with increased AMPA receptor (AMPAR) surface expression in the nucleus accumbens (NAc). This upregulation is withdrawal-dependent, as it is not detected on withdrawal day (WD) 1, but is observed on WD7-21. Its underlying mechanisms
Carrie R Ferrario et al.
Neuroscience letters, 490(3), 180-184 (2010-12-25)
We characterized the distribution of AMPA receptor (AMPAR) subunits and the transmembrane AMPA receptor regulatory proteins (TARPs) γ-2 and γ-4 in adult rat nucleus accumbens (NAc) using a method that separates plasma membranes into synaptic membrane-enriched and extrasynaptic membrane-enriched fractions.
Samuel W Centanni et al.
Alcoholism, clinical and experimental research, 38(11), 2800-2808 (2014-11-26)
The long-term consequences of adolescent alcohol abuse that persist into adulthood are poorly understood and have not been widely investigated. We have shown that intermittent exposure to alcohol during adolescence decreased the amplitude of GABAA receptor (GABAA R)-mediated tonic currents

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