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Key Documents

8.55009

Sigma-Aldrich

NovaSyn®TGR resin

Novabiochem®

Sinónimos:

NovaSyn TGR Solid Support Resin

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About This Item

UNSPSC Code:
12352209
NACRES:
NA.22

Quality Level

product line

NovaSyn® TG
Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

General description

An excellent acid labile support for Fmoc continuous flow and batch synthesis of peptide amides. This resin is prepared from 90 μm NovaSyn TG amino resin by derivatization with the modified Rink linker. It is supplied without Fmoc protection of the linker benzhydrylamine group as this has been found to improve stability. Cleavage is effected with 95% TFA.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Application

  • An overview of chemical synthesis of antiviral peptides: This study discusses the use of NovaSyn®TGR resin, among others, for peptide synthesis using the Fmoc strategy, particularly highlighting its application in synthesizing antiviral peptides. (Maharani & Muhajir, 2021).

Linkage

Replaces: 01-64-0060

Analysis Note

Color (visual): pale yellow to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in DMF): lot specific result
The base resin is a PEG-PS copolymer (90 µm) functionalised with the modified Rink linker.

Legal Information

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Artículos

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Protocolos

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

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