900859

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• Sinónimos: Bromo sulfonyl fluoride TMS-alkyne, Probe building block
• Fórmula empírica (notación de Hill): C₁₁H₁₂BrFO₂SSi
• Número de CAS: 2088829-15-4
• Peso molecular: 335.26
• Número MDL: MFCD31579818
• Código UNSPSC: 12352200
• NACRES: NA.22

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥95%
• Formulario: powder or crystals
• idoneidad de la reacción: reaction type: click chemistry
• temp. de almacenamiento: −20°C
• cadena SMILES: [Si](C)(C)(C)C#Cc1cc(cc(c1)Br)[S](=O)(=O)F
• InChI: 1S/C11H12BrFO2SSi/c1-17(2,3)5-4-9-6-10(12)8-11(7-9)16(13,14)15/h6-8H,1-3H3
• Clave InChI: CUUVPHAGWQDSCZ-UHFFFAOYSA-N

Descripción

Aplicación

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Otras notas

Technology Spotlight: Trifunctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable