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Merck

381667

Sigma-Aldrich

Diethylenetriaminepentaacetic acid gadolinium(III) dihydrogen salt hydrate

97%

Sinónimos:

Gadopentetic acid

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About This Item

Fórmula empírica (notación de Hill):
C14H20GdN3O10 · xH2O
Peso molecular:
547.57 (anhydrous basis)
MDL number:
UNSPSC Code:
12161600
PubChem Substance ID:
NACRES:
NA.22
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Quality Level

assay

97%

reaction suitability

core: gadolinium
reagent type: catalyst

mp

129 °C (dec.) (lit.)

SMILES string

[Gd+3].[H]O[H].OC(=O)CN(CCN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O)CC([O-])=O

InChI

1S/C14H23N3O10.Gd.H2O/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;1H2/q;+3;/p-3

InChI key

JBUMALASVLVYKI-UHFFFAOYSA-K

Application

Widely used metal ion complex for MRI used in the diagnosis of cerebral tumors,[1][2] CNS diseases, hepatic tumors,[2] pituitary adenomas,[3] multiple sclerosis, and blood-brain barrier impairment.[4][5]

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Chao Feng et al.
Experimental and therapeutic medicine, 13(6), 3535-3542 (2017-06-08)
The aim of the present study was to evaluate and compare the effectiveness of different imaging methods during follow-up of prostatic radiofrequency ablation. Prostatic radiofrequency ablation (RFA) was performed in 20 healthy beagle dogs. Various imaging examinations were used to
Magnetic resonance imaging in neurosarcoidosis.
A Greco et al.
Magnetic resonance imaging, 5(1), 15-21 (1987-01-01)
K Ohtomo et al.
Radiology, 163(1), 27-31 (1987-04-01)
Thirty-six patients with hepatic tumors (28 hepatocellular carcinomas, seven cavernous hemangiomas, one metastatic tumor) were examined with serial magnetic resonance (MR) imaging, after a bolus intravenous injection of 0.05 mmol/kg gadolinium-diethylenetriaminepentaacetic acid. A typical MR imaging pattern for hemangiomas (present
A J Dwyer et al.
Radiology, 163(2), 421-426 (1987-05-01)
To assess the role of magnetic resonance imaging in the evaluation of adrenocorticotropic-hormone (ACTH)-producing pituitary adenomas, and the effect of intravenously administered gadolinium-diethylenetriaminepentaacetic acid (DTPA) on lesion/pituitary contrast, imaging was performed in 13 patients with clinical and chemical evidence of
Christof Karmonik et al.
World neurosurgery, 105, 775-782 (2017-06-19)
Hemodynamics in cerebral aneurysms are currently investigated toward clinical efficacy using nonstandardized computational simulation techniques. At the same time, flow patterns and velocities are accessible by 4-dimensional phase contrast magnetic resonance imaging (4D pcMRI). Complexity of protocol design and imaging

Questions

  1. May I know the isotopes of the Gd in the compound, is it the natural Gd? Thanks!

    1 answer
    1. The isotopes for this material have not been determined. The gadolinium source is listed as synthetic or transformed.

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