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261394

Sigma-Aldrich

1,1-Dimethylurea

99%

Sinónimos:

N,N-Dimethylurea

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About This Item

Fórmula lineal:
(CH3)2NCONH2
Número de CAS:
598-94-7
Peso molecular:
88.11
EC Number:
209-957-0
MDL number:
MFCD00007959
UNSPSC Code:
12352100
PubChem Substance ID:
24855807
NACRES:
NA.22

assay

99%

form

solid

mp

178-183 °C (lit.)

solubility

water: soluble 5%, clear, colorless

SMILES string

CN(C)C(N)=O

InChI

1S/C3H8N2O/c1-5(2)3(4)6/h1-2H3,(H2,4,6)

InChI key

YBBLOADPFWKNGS-UHFFFAOYSA-N

Gene Information

human ... EPHX2(2053)
mouse ... Ephx2(13850)

General description

Nonlinear optical properties of 1,1-dimethylurea (N,N′ dimethylurea), have been evaluated through second-harmonic generation.

Application

1,1-Dimethylurea (N,N-dimethylurea) has been used in the Dowex-50W ion exchange resin-promoted synthesis of N,N′-disubstituted-4-aryl-3,4-dihydropyrimidinones.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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J W McDonald et al.
The American review of respiratory disease, 143(4 Pt 1), 806-809 (1991-04-01)
Eugenol, an extract of cloves, has been associated with pulmonary edema when inhaled from commercially available clove cigarettes. We tested the hypothesis that eugenol directly causes lung edema through oxidant-mediated mechanisms by infusing eugenol (0.1 and 1.0 mM) into isolated
W J Caspary et al.
Mutation research, 174(4), 285-293 (1986-08-01)
Methylisocyanate (MIC) induced mutagenic responses in the absence of exogenous activation in the mouse lymphoma cell forward mutation assay at concentrations as low as 8-24 microM. MIC produced predominantly small mutant colonies, suggesting the possibility of clastogenic activity. The intermediate
G P Meshram et al.
Mutation research, 279(4), 275-280 (1992-06-16)
Methyl isocyanate (MIC) in aqueous solution forms methylamine (MA) and N,N'-dimethylurea (DMU). MA in buffered system further converts into its salt form, methylamine hydrochloride (MAH). Therefore, MAH and DMU were evaluated for their mutagenic activity in the in vitro Ames
Nonlinear optical properties of N, N' dimethylurea.
Halbout JM, et al.
Applied Physics Letters, 37(10), 864-866 (2008)
S Sandler et al.
Acta pharmacologica et toxicologica, 53(5), 392-400 (1983-11-01)
The possible protective effects in vitro of the hydroxyl radical scavenger dimethyl urea (6 mg/ml) and the poly(ADP-ribose)synthetase inhibitors theophylline (5 mM) and nicotinamide (0.75 mg/ml) against streptozotocin (SZ) induced deterioration of islet metabolism were investigated using isolated mouse pancreatic
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