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Key Documents

AB9708

Sigma-Aldrich

Anti-PSD-95 Antibody

Chemicon®, from rabbit

Synonym(s):

Post synaptic density 95

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

rat ... Dlg4(29495)

Specificity

PSD-95 (Post synaptic density 95). By Western blot the antibody recognizes a band at ~95 kDa in rat brain microsomal preparation.

Immunogen

Synthetic peptide.

Application

Anti-PSD-95 Antibody detects level of PSD-95 & has been published & validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
Western blot: 0.1-1 μg/mL on rat brain microsomal preparation.

Optimal working dilutions must be determined by the end user.

Linkage

Replaces: 04-1066

Physical form

ImmunoAffinity Purified
Liquid in PBS with 0.1% sodium azide.

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Marta U Wołoszynowska-Fraser et al.
eNeuro, 8(5) (2021-08-22)
Retinoic acid (RA), a metabolite of vitamin A, has many physiological functions, and mounting evidence points to important roles in cognition. In vitro experiments indicate that RA is involved in homeostatic synaptic scaling in the hippocampus, which supports overall network
Marie Pronot et al.
Frontiers in molecular neuroscience, 14, 780535-780535 (2021-12-11)
Synapses are highly specialized structures that interconnect neurons to form functional networks dedicated to neuronal communication. During brain development, synapses undergo activity-dependent rearrangements leading to both structural and functional changes. Many molecular processes are involved in this regulation, including post-translational
Hong-Ru Chen et al.
JCI insight, 6(17) (2021-07-30)
The creatine transporter (CrT) maintains brain creatine (Cr) levels, but the effects of its deficiency on energetics adaptation under stress remain unclear. There are also no effective treatments for CrT deficiency, the second most common cause of X-linked intellectual disabilities.
Ram Kuwar et al.
Journal of Alzheimer's disease : JAD, 82(4), 1769-1783 (2021-07-06)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder, and the most common type of dementia. A growing body of evidence has implicated neuroinflammation as an essential player in the etiology of AD. Inflammasomes are intracellular multiprotein complexes and essential components
Ke Zhang et al.
Science signaling, 9(458), ra123-ra123 (2016-12-15)
Although the molecular mechanism is not clear, the clinically tested drug ketamine has rapid antidepressant action that does not require the multiple weeks of treatment needed for other antidepressant drugs to have an effect. We showed that ketamine potentiated Schaffer

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