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450243

Sigma-Aldrich

Sodium orthovanadate

99.98% trace metals basis

Synonym(s):

Trisodium vanadate

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About This Item

Linear Formula:
Na3VO4
CAS Number:
13721-39-6
Molecular Weight:
183.91
EC Number:
237-287-9
MDL number:
MFCD00003511
UNSPSC Code:
12161600
PubChem Substance ID:
24868233
NACRES:
NA.22

Quality Level

200

Assay

99.98% trace metals basis

form

solid

reaction suitability

core: vanadium
reagent type: catalyst

mp

850-866 °C (lit.)

SMILES string

[Na+].[Na+].[Na+].[O-][V]([O-])([O-])=O

InChI

1S/3Na.4O.V/q3*+1;;3*-1;

InChI key

IHIXIJGXTJIKRB-UHFFFAOYSA-N

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Application

Sodium orthovanadate (Na3VO4) can be used as a metal precursor in the synthesis of:
  • Vanadium-MCM-48 (V-MCM-48) by anion-exchange method. V-MCM-48 is used as a catalyst in oxidation of styrene to benzaldehyde.
  • Nanorods of vanadium oxide particles by glycothermal method.
  • Yttrium vanadate (YVO4) doped with colloidal europium.

Biochem/physiol Actions

An inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases.
Inhibits ATPase, alkaline phosphatase and tyrosine phosphatase. Decavanadate, which is formed at acidic pH, inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding to its receptor in brain tissue.

Packaging

Exhibits various biological and physiological effects in the human body

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Synthesis and characterizations of YVO4: Eu colloids.
Huignard A, et al.
Chemistry of Materials, 14(5), 2264-2269 (2002)
Synthesis and characterization of TM-MCM-48 (TM= Mn, V, Cr) and their catalytic activity in the oxidation of styrene.
Gomez S, et al.
J. Catal., 233(1), 60-67 (2005)
Yu Hasegawa et al.
The Journal of pharmacology and experimental therapeutics, 317(2), 875-881 (2006-02-08)
Vanadium is widely distributed in the environment and exhibits various biological and physiological effects in the human body. We previously documented the neuroprotective effect of sodium orthovanadate (SOV) against in rodents i.v. injected with 2 ml/kg 50 mM SOV just
Glycothermal synthesis of assembled vanadium oxide nanostructures for gas sensing.
Fu H, et al.
Journal of Nanoparticle Research, 14(6), 871-871 (2012)
A Morita et al.
Cell death and differentiation, 13(3), 499-511 (2005-09-03)
We previously reported that p42/SETbeta is a substrate for caspase-7 in irradiated MOLT-4 cells, and that treating the cells with sodium orthovanadate (vanadate) inhibits p42/SETbeta's caspase-mediated cleavage. Here, we initially found that the inhibitory effect of vanadate was due to
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