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Key Documents

SAB4500879

Sigma-Aldrich

Anti-GPRC6A antibody produced in rabbit

affinity isolated antibody

Synonym(s):

G-protein coupled receptor 33, G-protein coupled receptor family C group 6 member A, GPRC6A, hGPCR33, hGPRC6A

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100 μG
€346.00

€346.00

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100 μG
€346.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

€346.00

Please contact Customer Service for Availability

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 104 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

ELISA: 1:1000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

NCBI accession no.

Q5T6X5

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GPC6A(222545)

General description

Anti-GPRC6A Antibody detects endogenous levels of total GPRC6A protein.

G protein-coupled receptor class C group 6 member A (GPRC6A) belongs to C G protein-coupled receptors family. It is mapped to human chromosome 6q22.

Immunogen

The antiserum was produced against synthesized peptide derived from human GPRC6A.

Immunogen Range: 471-520

Biochem/physiol Actions

Mutations in G protein-coupled receptor class C group 6 member A (GPRC6A) modulates the activities and expression of cell surface. It also controls prostate cancer progression.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
61321

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Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function
J?rgensen S, et al.
The Journal of Biological Chemistry, 292(4), 1524-1534 (2017)
GPRC6A regulates prostate cancer progression
Pi M and Quarles LD
Prostate, 72(4), 399-409 (2012)
Replication and fine mapping for association of the C2orf43, FOXP4, GPRC6A and RFX6 genes with prostate cancer in the Chinese population
Long QZ, et al.
PLoS ONE, 7(5) (2012)

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