This product is prepared in 50mM Tris/HCl pH7.5, containing 0.1mM EGTA, 150mM NaCl, 0.03% Brij-35, 270mM sucrose, 1mM, benzamidine, 0.2mM PMSF, and 0.1% 2-mercaptoethanol.
14-573-M
Pim1 Protein, active, 10 µg
Active, N-terminal GST-tagged recombinant human full length Pim-1, for use in Kinase Assays.
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10 μG
€547.00
250 μG
€3,470.00
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10 μG
€547.00
250 μG
€3,470.00
About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.32
Recommended Products
biological source
human
Quality Level
recombinant
expressed in E. coli
mol wt
Mw 62 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
General description
N-terminal GST-tagged recombinant human full length Pim-1
Product Source: expressed in E. coli cells
Application
Research Category
Inflammation & Immunology
Inflammation & Immunology
Biochem/physiol Actions
Protein Target: Pim-1
Target Sub-Family: CAMK
Packaging
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-573M when ordering the 250 µg size.
Quality
routinely evaluated by phosphorylation of S6 Kinase/Rsk-2 Substrate Peptide 2
Physical form
Glutathione agarose affinity chromatography
Storage and Stability
6 months at -70°C
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Miriam López-Ramos et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(9), 3171-3185 (2010-04-20)
Protein kinase casein kinase 2 (CK2) is a serine/threonine kinase with evidence of implication in growth dysregulation and apoptosis resistance, making it a relevant target for cancer therapy. Several CK2 inhibitors have been developed showing variable efficiency, emphasizing the need
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