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880001M

Avanti

Chol-PEG600

Avanti Research™ - A Croda Brand 880001M, methylene chloride solution

Synonym(s):

Cholesterol-(polyethylene glycol-600)

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25 MG
€271.00

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25 MG
€271.00

About This Item

CAS Number:
27321-96-6
MDL number:
MFCD02685524
UNSPSC Code:
12352211
NACRES:
NA.25

€271.00

Please contact Customer Service for Availability
Request a Bulk Order

form

methylene chloride solution

packaging

pkg of 1 × 2.5 mL (880001M-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880001M

concentration

10 mg/mL (880001M-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

O(C1CCC2(C3C(C4C(C(CC4)C(CCCC(C)C)C)(CC3)C)CC=C2C1)C)CCO

InChI

1S/C29H50O2/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(31-18-17-30)13-15-28(22,4)27(24)14-16-29(25,26)5/h9,20-21,23-27,30H,6-8,10-19H2,1-5H3

InChI key

NPYXBHZQVNRAOF-UHFFFAOYSA-N

General description

Chol-PEG600, also known as cholesterol-(polyethylene glycol-600), is a derivative of cholesterol[1] and is a nonionic amphipathic lipid. Structurally, it comprises lipophilic cholesterol and covalently bound hydrophilic PEG.[2]

Biochem/physiol Actions

PEG-cholesterol is mainly used in preparation of lipoplexes for DNA transfection studies,[1][2] and liposomes for encapsulated drug delivery.[2]

Packaging

5 mL Clear Glass Sealed Ampule (880001M-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H336,H351

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

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Certificates of Analysis (COA)

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Poly (ethylene glycol)-cholesterol inhibits L-type Ca2+ channel currents and augments voltage-dependent inactivation in A7r5 cells
Ochi, R, et al.
Testing, 9(9) (2014)
Poly (ethylene glycol)-cholesterol inhibits L-type Ca2+ channel currents and augments voltage-dependent inactivation in A7r5 cells
Ochi, R, et al.
PLoS ONE, 9(9) (2014)
Rikuo Ochi et al.
PloS one, 9(9), e107049-e107049 (2014-09-10)
Cholesterol distributes at a high density in the membrane lipid raft and modulates ion channel currents. Poly(ethylene glycol) cholesteryl ether (PEG-cholesterol) is a nonionic amphipathic lipid consisting of lipophilic cholesterol and covalently bound hydrophilic PEG. PEG-cholesterol is used to formulate
CHOBIMALT: a cholesterol-based detergent
Howell S, et al.
Biochemistry, 49(44), 9572-9583 (2010)

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