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938238

Sigma-Aldrich

Silica

monodisperse, non-porous, 5 μm

Synonym(s):

Monodisperse silicon dioxide, Non-porous silica, Non-porous silicon dioxide, Silicon dioxide

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938238-2G
€343.00

€343.00

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938238-2G
€343.00

About This Item

Linear Formula:
SiO2
CAS Number:
7631-86-9
Molecular Weight:
60.08
MDL number:
MFCD00011232
UNSPSC Code:
12352309

€343.00

Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

form

powder

particle size

5 μm

pore size

non-porous

bp

2230 °C (lit.)

mp

>1600 °C (lit.)

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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Show Differences

1 of 4

This Item
938254938270904368
Silica monodisperse, non-porous, 5 μm

938238

Silica

Silica Monodisperse, non-porous, 40 µm

938254

Silica

Silica mesoporous, 100 μm particle size, pore size ~40 Å

938270

Silica

Silica monodisperse, non-porous, 10 μm

904368

Silica

form

powder

form

powder

form

mesoporous, powder

form

powder

mp

>1600 °C (lit.)

mp

>1600 °C (lit.)

mp

>1600 °C (lit.)

mp

>1600 °C (lit.)

pore size

non-porous

pore size

non-porous

pore size

~40 Å pore size

pore size

-

bp

2230 °C (lit.)

bp

2230 °C (lit.)

bp

2230 °C (lit.)

bp

2230 °C (lit.)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

General description

Our monodisperse, non-porous silica powder is a white powder composed of speherical particles, precisely engineered to achieve a monodisperse particle size of 5 µm with 99.99% purity. The microparticles do not contain any internal porosity or void spaces, making their surfaces impermeable to fluids or gases.

Application

Monodisperse, non-porous silica particles have several applications in various research areas including drug delivery, molecular imaging, and environmental remediation. Owing to their stable chemical structure, ease of surface modification, and affinity toward various biomolecules, silica microparticles are an attractive platform for bioconjugation of drugs, proteins, DNA, and other biomarkers. Consequently, non-porous silica particles and their bioconjugates are used in biomedical applications for delivering or isolating drugs, proteins, polynucleotides, and more. Bioconjugation of non-porous silica often facilitates imaging techniques including optical imaging (fluorescence and bioluminescence), magnetic resonance imaging (MRI), radionuclide imaging, computed tomography (CT), ultrasound, photoacoustic imaging, and Raman imaging.[1],[2]Apart from these applications, these monodisperse particles are also used in analytical applications, such as the stationary phase in columns for advanced, high-performance liquid chromatography.[3]

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW0590

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Nonporous Silica Nanoparticles for Nanomedicine Application
Tang L, et al.
Nano Today, 8, 290-312 (2013)
Safety of Nonporous Silica Nanoparticles in Human Corneal Endothelial Cells
Kim J Y, et al
Scientific Reports, 7, 14566-14566 (2017)
Core-shell particles lead the way to renewing high-performance liquid chromatography
Gonzalez-Ruiz V, et al
TrAC, Trends in Analytical Chemistry, 64, 17-28 (2015)
Sean E Lehman et al.
Langmuir : the ACS journal of surfaces and colloids, 32(3), 731-742 (2015-12-31)
Understanding complex chemical changes that take place at nano-bio interfaces is of great concern for being able to sustainably implement nanomaterials in key applications such as drug delivery, imaging, and environmental remediation. Typical in vitro assays use cell viability as
Nano-Bio Interactions of Porous and Nonporous Silica Nanoparticles of Varied Surface Chemistry: A Structural, Kinetic, and Thermodynamic Study of Protein Adsorption from RPMI Culture Medium
Lehman S, et al.
Langmuir, 32, 731-742 (2016)
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